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Monoclonal Anti-Na⁺/Ca²⁺ Exchanger antibody produced in mouse

Name: Monoclonal Anti-Na<SUP>+</SUP>/Ca<SUP>2+</SUP> Exchanger antibody produced in mouse
Brand: SIGMA
Price: 718 USD
Availability: InStock

clone C2C12

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100 μL	Check Cart for Availability	$718.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01865491

Conjugate:

unconjugated

Clone:

C2C12, monoclonal

Application:

IHC (f), IP, WB

Citations:

$718.00

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody product type

primary antibodies

clone

C2C12, monoclonal

form

liquid

mol wt

antigen 120 kDa (mature exchanger), antigen 160 kDa (non-reduced), antigen 70 kDa (proteolytic fragment)

species reactivity

human, rat, canine, rabbit, guinea pig

technique(s)

immunohistochemistry (frozen sections): 1:200, immunoprecipitation (IP): suitable, western blot: 1:1,000

isotype

IgM

UniProt accession no.

P32418

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SLC8A1(6546)

Description

General description

Na⁺/Ca²⁺ exchanger is also known as solute carrier family 8 member A1 (SLC8A1) and is present in the plasma membrane. It is predicted to have nine transmembrane segments and the gene encoding SLC8A1 has three promoters.

Immunogen

dog cardiac Na⁺/Ca²⁺ exchanger. The epitope is in the region of amino acids 371-525, which is on the intracellular side of the plasma membrane.

Biochem/physiol Actions

Na⁺/Ca²⁺ exchanger (SLC8A1, solute carrier family 8 member A1) is involved in Ca²⁺ homeostasis. Depending on physiological conditions prevailing in the cell, it can either pump out Na⁺ or Ca²⁺.

The antibody reacts specifically with Na⁺/Ca²⁺ exchanger in kidney and cardiac tissues. By immunohistology, staining of the plasma membrane and intense staining of the cardiac T-tubular membrane is observed. The antibody is not recommended for immunoblotting of rat tissues.

Physical form

Solution in phosphate buffered saline, 1 mg/ml BSA containing 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	A273	A275	SAB4200415
Sigma-Aldrich N216 Monoclonal Anti-Na⁺/Ca²⁺ Exchanger antibody produced in mouse	Sigma-Aldrich A273 Monoclonal Anti-Na⁺/K⁺ ATPase (α3 Subunit) antibody produced in mouse	Sigma-Aldrich A275 Monoclonal Anti-Na⁺/K⁺ ATPase (α1 Subunit) antibody produced in mouse	Sigma-Aldrich SAB4200415 Anti-NEZHA antibody, Mouse monoclonal
description clone C2C12	description 1 mg/mL, clone XVIF9-G10, ascites fluid	description clone 9A-5, ascites fluid	description clone NEZHA-1, purified from hybridoma cell culture
clone C2C12, monoclonal	clone XVIF9-G10, monoclonal	clone 9A-5, monoclonal	clone NEZHA-1, monoclonal
biological source mouse	biological source mouse	biological source mouse	biological source mouse
Gene Information human ... SLC8A1(6546)	Gene Information human ... ATP1A3(478) rat ... Atp1a3(24213)	Gene Information human ... ATP1A1(476) rat ... Atp1a1(24211)	Gene Information human ... CAMSAP3(57662) mouse ... Camsap3(69697)
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
species reactivity human, rat, canine, rabbit, guinea pig	species reactivity human, rat, monkey, sheep, rabbit, guinea pig, canine	species reactivity rat, human, canine, avian	species reactivity canine, human
mol wt antigen 160 kDa (non-reduced), antigen 70 kDa (proteolytic fragment), antigen 120 kDa (mature exchanger)	mol wt antigen ~110 kDa	mol wt antigen ~110 kDa	mol wt antigen ~150 kDa

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Storage Class

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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