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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $407.00 |
About This Item
Empirical Formula (Hill Notation):
C27H45IN2
CAS Number:
Molecular Weight:
524.56
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
$407.00
Check Cart for Availability
Quality Segment
assay
≥98% (HPLC)
form
solid
color
white to off-white
mp
88.2-94.9 °C
solubility
DMSO: >20 mg/mL
storage temp.
−20°C
SMILES string
[I-].CCCCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C
InChI
1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1
InChI key
RVWOHCBHAGBLLT-UHFFFAOYSA-M
Biochem/physiol Actions
NH125 exhibits anti-proliferation activity against many cancer cells. It also exhibits antibacterial effects by inhibiting bacterial histidine protein kinase.
NH125 is a novel plant histidine kinase inhibitor and selective mammalian eurkaryotic elongation factor-2 kinase (eEF-2K).
Packaging
Packaged under nitrogen.
Analysis Note
IC50 = 60 nM for eEF-2 kinase vs protein kinase C (IC50= 7.5 μM), protein kinase A (IC50= 80 μM), and calmodulin-dependent kinase II IC50 > 100 μM).
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC), solid | description 98% | description ≥97.0% | description ≥97.0% (HPLC) |
| form solid | form crystals | form solid | form - |
| assay ≥98% (HPLC) | assay ≥98.0% (HPLC), 98% | assay ≥97.0% | assay ≥97.0% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. - | storage temp. - | storage temp. - |
| solubility DMSO: >20 mg/mL | solubility - | solubility - | solubility - |
| color white to off-white | color - | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Gloves
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