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O0391

Olopatadine hydrochloride

≥98% (HPLC)

Synonym(s):

(11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride, AL-4943A, KW-4679, Opatanol, Patanol

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Size/SKUAvailabilityPrice
10 mg

Available to ship TODAY

$98.20
50 mg

Available to ship TODAY

$390.00

About This Item

Empirical Formula (Hill Notation):
C21H23NO3·HCl
CAS Number:
Molecular Weight:
373.87
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$98.20


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Quality Segment

assay

≥98% (HPLC)

form

solid

solubility

H2O: ≥20 mg/mL

storage temp.

room temp

SMILES string

Cl.CN(C)CC\C=C1\c2ccccc2COc3ccc(CC(O)=O)cc13

InChI

1S/C21H23NO3.ClH/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24;/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24);1H/b18-8-;

InChI key

HVRLZEKDTUEKQH-NOILCQHBSA-N

Gene Information

human ... HRH1(3269)

Biochem/physiol Actions

Olopatadine is a dual acting histamine H1-receptor antagonist and mast cell stabilizer.
Olopatadine is a histamine H1 receptor antagonist and mast cell stabilizer. The low level of occupancy H1 receptors in the brain explains the low sedation effect of olopatidine. It is believed that olopatidine is a substrate for P-glycoprotein, which limits its brain penetration.

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This Item
PHR306914784031478425
description

≥98% (HPLC)

description

pharmaceutical secondary standard, certified reference material

description

United States Pharmacopeia (USP) Reference Standard

description

United States Pharmacopeia (USP) Reference Standard

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

form

solid

form

-

form

-

form

-

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

-

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

−20°C

solubility

H2O: ≥20 mg/mL

solubility

-

solubility

-

solubility

-

Gene Information

human ... HRH1(3269)

Gene Information

-

Gene Information

human ... HRH1(3269)

Gene Information

-


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Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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