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P0749

Anti-Potassium Channel Kv11.1 Extracellular antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-HERG, Anti-KCNH2

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200 μL
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$854.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD02097212
Conjugate:
unconjugated
Clone:
polyclonal
Application:
FACS, ICC, WB
Citations:
3

$854.00

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biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

flow cytometry: 2-8 μg using live intact K562 (human chronic myelogenous leukemia) cells (per 106 cells), immunocytochemistry: 1:25, western blot: 1:200 using HEK-KV11.1 transfected cells

UniProt accession no.

Q12809

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCNH2(3757)
mouse ... Kcnh2(16511)
rat ... Kcnh2(117018)

General description

The K+ channel family has been sub-grouped in to 2 TM, 4 TM and 6 TM K+ channels based on the number of transmembrane domains. The voltage-gated Potassium or Kv channels belong to the 6 TM K+ channel family that also include other sub-types such as the hERG, KCNQ, and EAG channels. Kv11.1 belongs to the EAG family and facilitates the repolarization of normal action potential in heart muscles. Genetic alterations in Kv11.1 can cause heart disorders such as long QT syndrome, sudden cardiac death and arhythmias. Kv11.1 also regulates cell growth and hence may be studied as a target for cancer treatment. Anti-Potassium channel Kv11.1 extracellular antibodies are specific to Kv11.1.

Immunogen

peptide AFLLKETEEGPPATEC corresponding to residues 430-445 of human KV11.1. This sequence has 11/16 residues identical in mouse and rat and has 15/16 residues identical in rabbit and dog.

Application

Anti-Potassium channel Kv11.1 extracellular antibodies may be used in immunofluorescence microscopy . It may also be used for the detection of Kv11.1 by techniques such as immunocytochemistry, flow cytometry using live intact K562 (human chronic myelogenous leukemia) cells and western blotting.

Physical form

Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-Potassium Channel Kv11.1 Extracellular antibody produced in rabbit affinity isolated antibody, lyophilized powder

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Anti-Potassium Channel Kv11.1 (HERG) Extracellular−FITC antibody produced in rabbit affinity isolated antibody, lyophilized powder

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Anti-Potassium Channel Kv11.2 (erg2) antibody produced in rabbit

Anti-Potassium Channel Kv1.2 Antibody, clone K14/16 clone K14/16, from mouse

Sigma-Aldrich

MABN77

Anti-Potassium Channel Kv1.2 Antibody, clone K14/16

description

affinity isolated antibody, lyophilized powder

description

affinity isolated antibody, lyophilized powder

description

affinity isolated antibody, lyophilized powder

description

clone K14/16, from mouse

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified antibody

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

conjugate

unconjugated

conjugate

FITC conjugate

conjugate

unconjugated

conjugate

unconjugated

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

UniProt accession no.

Q12809

UniProt accession no.

Q12809

UniProt accession no.

O54853

UniProt accession no.

P63142

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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