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P3449

Phloridzin dihydrate

From apple wood, ≥99% (HPLC), Na+-glucose cotransport inhibitor, powder

동의어(들):

1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, Phloretin 2′-β-D-glucopyranoside, Phloretin 2′-β-D-glucoside, Phlorizin dihydrate

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크기 선택

보기 변경
팩 크기/SKU재고 정보가격 (VAT 별도)
100 mg
구입 가능 여부는 고객센터에 문의하십시오.
₩124,744
500 mg
구입 가능 여부는 고객센터에 문의하십시오.
₩128,601
1 g
구입 가능 여부는 고객센터에 문의하십시오.
₩269,381
5 g
구입 가능 여부는 고객센터에 문의하십시오.
₩772,517
10 g
구입 가능 여부는 고객센터에 문의하십시오.
₩1,097,215

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C21H24O10 · 2H2O
CAS 번호:
Molecular Weight:
472.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-487-1
MDL number:
Beilstein/REAXYS Number:
66621
Assay:
≥99% (HPLC)
Form:
powder

₩124,744


구입 가능 여부는 고객센터에 문의하십시오.

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제품 이름

Phloridzin dihydrate, from apple wood, ≥99% (HPLC)

biological source

apple wood

Quality Segment

assay

≥99% (HPLC)

form

powder

mp

113-114 °C (lit.)

SMILES string

O.O.OC[C@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H24O10.2H2O/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10;;/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2;2*1H2/t16-,18-,19+,20-,21-;;/m1../s1

InChI key

XQWBNXSENPTIDY-YXMARJSJSA-N

Application

Phloridzin dihydrate has been used as:
  • a Na+-glucose cotransport inhibitor to test its effect in lowering blood glucose
  • a hexose carrier inhibitor to prevent glucose derivative 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) uptake in sycamore cells
  • a non-specific sodium-glucose co-transporter 2 (SGLT2) inhibitor in embryonic cardiomyocyte cell line H9C2 to investigate its protective effect on Dox-induced cytotoxicity

Biochem/physiol Actions

Phloridzin is a glycoside present in the leaves and bark of apple. It is also present in peel and pulp of the apple fruit. Phloridzin belongs to the dihydrochalcones class of compounds. Lactase catabolizes phloridzin to phloretin and glucose in small intestine epithelial cells. Phloridzin is an antidiabetic agent and is equally bioavailable as phloretin.

Features and Benefits

Used to induce experimental glycosuria.

Other Notes

Dihydrochalcone glycoside found in apple tree

유사한 품목 비교

전체 비교 보기

차이점 표시

1 of 1

이 품목
274313P7912PHL80513
Phloridzin phyproof® Reference Substance

PHL80513

Phloridzin

description

from apple wood, ≥99% (HPLC)

description

99%

description

≥99%

description

phyproof® Reference Substance

assay

≥99% (HPLC)

assay

99%

assay

≥99%

assay

≥98.0% (HPLC)

form

powder

form

powder

form

powder

form

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

biological source

apple wood

biological source

-

biological source

-

biological source

-

mp

113-114 °C (lit.)

mp

113-114 °C (lit.)

mp

~260 °C

mp

-


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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