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P3510

Papaverine hydrochloride

≥98% (titration by HCL04), powder, cerebral vasodilator

Synonym(s):

6,7-Dimethoxy-1-veratrylisoquinoline hydrochloride

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Size/SKUAvailabilityPrice
5 g
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$57.00
25 g
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$187.00
100 g
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$393.00

About This Item

Empirical Formula (Hill Notation):
C20H21NO4 · HCl
CAS Number:
Molecular Weight:
375.85
MDL number:
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-502-1
Beilstein/REAXYS Number:
3921435
Assay:
≥98%
Form:
powder

$57.00


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Product Name

Papaverine hydrochloride, powder

assay

≥98%

Quality Segment

form

powder

color

white

solubility

H2O: 25 mg/mL

SMILES string

COC1=C(OC)C=C(C(CC2=CC(OC)=C(OC)C=C2)=NC=C3)C3=C1.Cl

InChI

1S/C20H21NO4.ClH/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16;/h5-8,10-12H,9H2,1-4H3;1H

InChI key

UOTMYNBWXDUBNX-UHFFFAOYSA-N

Gene Information

human ... PDE4B(5142)

General description

Papaverine hydrochloride belongs to the group of benzylisoquinoline alkaloid. It is obtained from opium poppy.

Application

Papaverine hydrochloride has been used:
  • in oxygenated Krebs solution for tissue mechanics analysis
  • as a vasodilator in heparinized horse serum in tissue uptake technique
  • as an inhibitor of H-MPP+ uptake into stably transfected 293 cells expressing either extraneuronal monoamine transporter (EMT) human or EMT rat

Biochem/physiol Actions

Papaverine is originally used to resolve male impotence.
Smooth muscle relaxant and cerebral vasodilator; phosphodiesterase inhibitor.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
BP2771496008P7791
description

powder

description

British Pharmacopoeia (BP) Reference Standard

description

United States Pharmacopeia (USP) Reference Standard

description

≥99.0% (HPLC)

form

powder

form

powder

form

-

form

powder

assay

≥98%

assay

-

assay

-

assay

≥99.0% (HPLC)

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

100

solubility

H2O: 25 mg/mL

solubility

-

solubility

-

solubility

H2O: 0.5 mg/mL, methanol: 6 mg/mL, dilute aqueous acid: insoluble

color

white

color

-

color

-

color

-

Gene Information

human ... PDE4B(5142)

Gene Information

-

Gene Information

-

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)


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Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Codes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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