The stability of this compound in solution has not been determined. However, various sources recommend that solutions not be stored for more than 1 day. If necessary, stock solutions may be stored in aliquots at -20°C for up to 1 month. This information has not been validated.
P4620
PD 146176
≥98% (HPLC), solid
Synonym(s):
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $230.00 |
25 mg | Check Cart for Availability | $653.00 |
About This Item
Empirical Formula (Hill Notation):
C15H11NS
CAS Number:
Molecular Weight:
237.32
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality Segment
assay
≥98% (HPLC)
form
solid
color
white to beige
solubility
DMSO: soluble >10 mg/mL, H2O: insoluble
SMILES string
C1Sc2ccccc2-c3[nH]c4ccccc4c13
InChI
1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2
InChI key
ZGOOPZVQMLHPFM-UHFFFAOYSA-N
Gene Information
human ... ALOX15(246)
mouse ... ALOX15(11687)
rat ... ALOX15(81639)
Application
PD 146176 has been used to study its influence on ex vivo leukotriene B4 (LTB4) and lipoxin A4 (LXA4) secretion in adipose tissue.
Biochem/physiol Actions
15-Lipoxygenase inhibitor
PD 146176 blocks neuroprotectin D1 (NPD1) and eicosanoid synthesis by inhibiting the 5-lipoxygenase-1 (15-LOX-1) enzyme.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC), solid | description recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE) | description purified immunoglobulin, buffered aqueous solution | description Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution |
| assay ≥98% (HPLC) | assay ≥60% (SDS-PAGE) | assay - | assay - |
| form solid | form aqueous solution | form buffered aqueous solution | form buffered aqueous glycerol solution |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| solubility H2O: insoluble, DMSO: soluble >10 mg/mL | solubility - | solubility - | solubility - |
| color white to beige | color - | color - | color - |
| Gene Information human ... ALOX15(246) | Gene Information human ... ALOX15(246) | Gene Information human ... ALOX15(246) | Gene Information human ... ALOX15(246) |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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Buongiorno, dopo aver risospeso la polvere, dove è meglio conservarla? Grazie
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