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Anti-Potassium Channel K_ir2.1 antibody produced in rabbit

Name: Anti-Potassium Channel K<SUB>ir</SUB>2.1 antibody produced in rabbit
Brand: SIGMA
Price: 399 USD
Availability: InStock

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-ATFB9, Anti-HHBIRK1, Anti-HHIRK1, Anti-IRK1, Anti-KIR2.1, Anti-LQT7, Anti-SQT3

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Size/SKU	Availability	Price
0.05 mL	Check Cart for Availability	$375.00 $399.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD02686542

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB CL

Citations:

$399.00

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat

technique(s)

immunohistochemistry: suitable, western blot (chemiluminescent): 1:200

UniProt accession no.

Q64273

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCNJ2(3759)
mouse ... Kcnj2(16518)
rat ... Kcnj2(29712)

Description

General description

Potassium voltage-gated channel subfamily J member 2 (KCNJ2) is an inward-rectifying potassium channel. This tetrameric protein possesses two transmembrane helix domains (M1 and M2), an ion-selective P-loop between M1 and M2 and cytoplasmic amino and carboxy-terminal domains. The gene encoding KCNJ2 is localized on human chromosome 17q24.3.

Immunogen

synthetic peptide corresponding to amino acids 392-410 of human Kir2.1 (with additional N-terminal cysteine). This epitope is identical in rabbit, bovine, pig, and guinea pig and highly homologous in rat, mouse and chicken.

Biochem/physiol Actions

Potassium voltage-gated channel subfamily J member 2 (KCNJ2) has been shown to have a role in the differentiation and proliferation of bone marrow-derived macrophages (BMDM) in mice. It allows the inward movement of K⁺ into the cell and maintains its balance. Mutations in the KCNJ2 gene have been linked to Andersen-Tawil syndrome.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, 1% bovine serum albumin, and 0.025% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	P8122	SAB5200027	HPA029109
Sigma-Aldrich P6102 Anti-Potassium Channel K_ir2.1 antibody produced in rabbit	Sigma-Aldrich P8122 Anti-Potassium Channel K_IR3.2 (GIRK2) antibody produced in rabbit	Sigma-Aldrich SAB5200027 Monoclonal Anti-KCNJ2 antibody produced in mouse	Sigma-Aldrich HPA029109 Anti-KCNJ2 antibody produced in rabbit
description affinity isolated antibody, lyophilized powder	description affinity isolated antibody, lyophilized powder	description clone S112B-14, 1 mg/mL, purified immunoglobulin	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
biological source rabbit	biological source rabbit	biological source mouse	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
form lyophilized powder	form lyophilized powder	form buffered aqueous glycerol solution	form buffered aqueous glycerol solution
clone polyclonal	clone polyclonal	clone S112B-14, monoclonal	clone polyclonal

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Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H312 + H332,H412

Precautionary Statements

P261 - P271 - P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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