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P6500

Pentylenetetrazole

≥99% (GC), powder, CNS stimulant

Synonym(s):

α,β-Cyclopentamethylenetetrazole, 1,5-Pentamethylenetetrazole, 6,7,8,9-Tetrahydro-5H-tetrazolo[1,5-a]azepine, Metrazole

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Size/SKUAvailabilityPrice
25 g

Available to ship TODAYfromMILWAUKEE

$108.00
50 g

Available to ship TODAYfromMILWAUKEE

$218.00
100 g

Available to ship TODAYfromMILWAUKEE

$403.00

About This Item

Empirical Formula (Hill Notation):
C6H10N4
CAS Number:
Molecular Weight:
138.17
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-219-3
MDL number:
Form:
powder

$108.00


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Product Name

Pentylenetetrazole,

form

powder

Quality Segment

bp

194 °C/12 mmHg (lit.)

mp

59-61 °C (lit.)

storage temp.

−20°C

SMILES string

C1CCc2nnnn2CC1

InChI

1S/C6H10N4/c1-2-4-6-7-8-9-10(6)5-3-1/h1-5H2

InChI key

CWRVKFFCRWGWCS-UHFFFAOYSA-N

General description

Pentylenetetrazole (PTZ) is a tetrazole derivative and inhibitor of the γ aminobutyric acid (GABAA) and its receptor complex. PTZ is a convulsing agent used for inducing seizures. It can traverse the blood-brain barrier.

Application

Pentylenetetrazole has been used to induce seizures in zebra fish larvae, mice, and male wistar rats.

Biochem/physiol Actions

Pentylenetetrazole is a non-specific central nervous system (CNS) stimulant and convulsant. PTZ induces oxidative stress and increases cortical malondialdehyde content and affects hippocampus, resulting in seizures.

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description

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description

The APE1 Inhibitor III controls the biological activity of APE1. This small molecule/inhibitor is primarily used for Cell Structure applications.

description

-

description

-

form

powder

form

solid

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

bp

194 °C/12 mmHg (lit.)

bp

-

bp

-

bp

-

mp

59-61 °C (lit.)

mp

-

mp

-

mp

-


pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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Questions

1–4 of 4 Questions  
  1. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  2. How do I solubilize Product P6500, Pentylenetetrazole?

    1 answer
    1. We test the solubility of this compound at a concentration of 50 mg/mL in water.

      Helpful?

  3. Can Product P6500, Pentylenetetrazole, be used to induce convulsions?

    1 answer
    1. Pentylenetetrazole induced convulsions have been reported by De Sarro G. et al., in Eur. J. Pharmacol., 368(2-3),149-159 (1999).

      Helpful?

  4. What is the solution stability for Product P6500, Pentylenetetrazole?

    1 answer
    1. We do not have any solution stability information for this product.  It is always best to make a fresh solution. If this is not possible, you can try storing solution in single use aliquots at -20°C.

      Helpful?

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