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Monoclonal Anti-PSTAIR antibody produced in mouse

Name: Monoclonal Anti-PSTAIR antibody produced in mouse
Brand: SIGMA
Price: 572 USD
Availability: InStock

clone PSTAIR, ascites fluid

Synonym(s):

Anti-CDC2

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Size/SKU	Availability	Price
100 μL	Check Cart for Availability	$572.00
0.2 mL	Available to ship TODAYfromMILWAUKEE	$727.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.43

MDL number:

MFCD00677382

Conjugate:

unconjugated

Clone:

PSTAIR, monoclonal

Application:

ELISA (i), IP, WB

Citations:

$572.00

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

PSTAIR, monoclonal

mol wt

antigen 33-34 kDa

contains

15 mM sodium azide

species reactivity

mouse, Japanese quail, human, amago salmon, eel, starfish, lily, carp, onion, goldfish, monkey, Xenopus, ciliates

technique(s)

immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1:4,000 using a COS-7 cell extract

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CDC2(983)
mouse ... Cdc2a(12534)

Description

General description

In every eukaryote examined, CDKs contain an evolutionary conserved 16 amino acid sequence called PSTAIR (EGVPSTAIREISLLKE) which distinguishes them from other protein kinases. The PSTAIR motif is involved in complex formation with cyclins. The availability of monoclonal antibody reacting specifically with the PSTAIR sequence enables the subcellular detection and localization of the various CDKs and examination of substrate interactions, in a variety of organisms.

Monoclonal Anti-PSTAIR (mouse IgG1 isotype) is derived from the PSTAIR hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. Cyclin-dependent kinase 1 (CDC2/CDK1) belongs to the Ser/Thr protein kinase family. It is located on human chromosome 10q21.

Immunogen

synthetic 16 amino acid oligopeptide containing the PSTAIR sequence conjugated to BSA.

Application

Monoclonal Anti-PSTAIR antibody produced in mouse has been used in:

western blot analysis
enzyme-linked immunosorbent assay (ELISA)
immunoprecipitation

Mouse monoclonal clone PSTAIR anti-PSTAIR antibody may be used for the localization of cyclin-dependent kinases containing the PSTAIR motif using various immunochemical assays including ELISA, immunoblot and immunoprecipitation.

Biochem/physiol Actions

Cyclin-dependent kinase 1 (CDC2/CDK1) controls various mitotic processes including the reorganization of the cytoskeleton, chromosome segregation, and formation and separation of daughter cells. It is essential for the multiplication of mammalian cell. It participates in tumorigenesis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB4200861	SAB4503707	SAB3501217
Sigma-Aldrich P7962 Monoclonal Anti-PSTAIR antibody produced in mouse	Sigma-Aldrich SAB4200861 Anti-PSTAIR antibody, Mouse monoclonal	Sigma-Aldrich SAB4503707 Anti-CDC2 antibody produced in rabbit	Sigma-Aldrich SAB3501217 Anti-Pst1 antibody produced in rabbit
description clone PSTAIR, ascites fluid	description clone PSTAIR, purified from hybridoma cell culture	description affinity isolated antibody	description affinity isolated antibody
antibody form ascites fluid	antibody form purified from hybridoma cell culture	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Gene Information human ... CDC2(983) mouse ... Cdc2a(12534)	Gene Information -	Gene Information human ... CDK1(983)	Gene Information Saccharomyces cerevisiae ... PST1(851625)
clone PSTAIR, monoclonal	clone PSTAIR	clone polyclonal	clone polyclonal
conjugate unconjugated	conjugate -	conjugate unconjugated	conjugate unconjugated
biological source mouse	biological source -	biological source rabbit	biological source rabbit
species reactivity mouse, Japanese quail, human, amago salmon, eel, starfish, lily, carp, onion, goldfish, monkey, Xenopus, ciliates	species reactivity rat, monkey, human, mouse	species reactivity human, rat, mouse	species reactivity yeast

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Storage Class

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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