Documentos clave

Ver Toda la documentación

Saltar a

P8232

Anti-P2X₇ Purinergic Receptor antibody produced in rabbit

Name: Anti-P2X<SUB>7</SUB> Purinergic Receptor antibody produced in rabbit
Brand: SIGMA
Price: 951 USD

affinity isolated antibody, lyophilized powder

Sinónimos:

Anti-P2X₇ Antibody, P2X₇ Receptor Detection, Rabbit Anti-P2X₇

para ver los precios por organización y contrato.

Seleccione un Tamaño

Cambiar Vistas

A ustedes/SKU	Disponibilidad	Precio
0.2 mL	Comprobar disponibilidad del carrito	$951.00

Acerca de este artículo

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD02097118

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB

Citations:

$951.00

Comprobar disponibilidad del carrito

Está disponible un anticuerpo recombinante y sin conservantes para su diana. Pruebe ZRB1755

Servicio técnico

¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.

Permítanos ayudarle

Propiedades

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human, mouse, rat

technique(s)

immunohistochemistry: suitable, western blot: 1:200-1:1,000

UniProt accession no.

Q99572

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... P2RX7(5027)
mouse ... P2rx7(18439)
rat ... P2rx7(29665)

Descripción

General description

Purinergic receptor P2X₇ is an ATP-gated cation channel. It is expressed in retinal pigmented epithelium and neural retina. The gene encoding this protein is localized on human chromosome 12.

Immunogen

Peptide (C)KIRKEFPKTQGQYSGFKYPY, corresponding to amino acid residues 576-595 of rat P2X7 Receptor (Accession Q64663). Intracellular, C-terminus.

Application

Anti-P2X7 Purinergic Receptor antibody produced in rabbit has been used in

immunoprecipitation[1]
immunofluorescence and confocal microscopy[1]
western blotting[2]

Biochem/physiol Actions

Purinergic receptor P2X₇ has a role in immunological processes. It has a role during oxidative stress under pathological conditions. The channel is permeable to Na⁺, Ca²⁺ and K⁺. Prolonged activation of the channel under some pathological conditions leads to the passage of large molecules and ultimately cell death. P2X7 may be involved in the release of interleukin-1β (IL-1β) and indirectly initiate an inflammatory cascade.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

Preparation Note

Prior to reconstitution, store at –20°C. After reconstitution, the stock antibody solution may be stored at 2–8°C for up to two weeks. For extended storage, freeze at -20°C, or below, in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. Centrifuge all antibody preparations before use (10,000 x g 5 min). Working dilution samples should be discarded if not used within 12 hours.

Other Notes

In order to obtain the best results using various techniques and preparations, we recommend determining the optimal working dilutions by titration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Comparar elementos similares

Ver comparación completa

Mostrar Diferencias

1 of 1

Este artículo	P7857	P8997	SAB2501287
Sigma-Aldrich P8232 Anti-P2X₇ Purinergic Receptor antibody produced in rabbit	Sigma-Aldrich P7857 Anti-P2X₁ Purinergic Receptor antibody produced in rabbit	Sigma-Aldrich P8997 Anti-Purinergic Receptor P2X₇ (extracellular)−FITC antibody produced in rabbit	Sigma-Aldrich SAB2501287 Anti-P2RX7 (N-terminal) antibody produced in goat
conjugate unconjugated	conjugate unconjugated	conjugate FITC conjugate	conjugate unconjugated
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
biological source rabbit	biological source rabbit	biological source rabbit	biological source goat
form lyophilized powder	form lyophilized powder	form lyophilized powder	form buffered aqueous solution
technique(s) immunohistochemistry: suitable, western blot: 1:200-1:1,000	technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot (chemiluminescent): 1:200	technique(s) flow cytometry: 10 μg/test using Jurkat T-cells	technique(s) flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

Still not finding the right product?

Pruebe nuestra Herramienta de selección de productos para limitar sus opciones

Clase de almacenamiento

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c