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PLA0016

Rabbit anti-MDC1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

Em:AB023051.5, KIAA0170, NFBD1, homologue to Drosophila photoreceptor protein calphotin, mediator of DNA-damage checkpoint 1, nuclear factor with BRCT domains 1

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Size/SKUAvailabilityPrice
100 μL
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$540.00

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
2

$540.00


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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

technique(s)

immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:2000-1:10000

accession no.

NP_055456.1

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... MDC1(9656)

Immunogen

The epitope recognized by PLA0016 maps to a region between residues 475 and 525 of human Mediator of DNA Damage Checkpoint 1 using the numbering given in entry NP_055456.1 (GeneID 9656).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

MDC1 is required for the S- and G2/M-checkpoint-mediated cell cycle arrest in response to DNA damage. MDC1 interacts with H2AX near sites of DNA double-strand breaks and recruits ATM kinase to foci of DNA damage. MDC1 also appears to regulate the function of other proteins involved in the DNA damage checkpoint such as BRCA1 and Chk2.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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conjugate

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unconjugated

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biological source

rabbit

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biological source

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biological source

rabbit

antibody form

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antibody form

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antibody form

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antibody form

affinity isolated antibody

clone

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clone

polyclonal

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polyclonal

species reactivity

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species reactivity

monkey, human

species reactivity

human

species reactivity

human

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


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Storage Class

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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