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PLA0054

Goat anti-Chk1 Antibody, Affinity Purified

Synonym(s):

1, CHK1, CHK1 (checkpoint; S.pombe) homolog, CHK1 checkpoint homolog, CHK1 checkpoint homolog (S. pombe), Checkpoint, Chk1-S, S. pombe, cell cycle checkpoint kinase, checkpoint kinase-1, homolog of

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Size/SKUAvailabilityPrice
100 μL
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$637.00

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
4

$637.00


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biological source

goat

Quality Segment

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

technique(s)

western blot: 1:2,500- 1:15,000

accession no.

NP_001265.1

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

goat ... Chk1(1111)

Immunogen

The epitope recognized by PLA0054 maps to a region between residues 200 and 250 of human Checkpoint Kinase 1 using the numbering given in entry NP_001265.1 (GeneID 1111).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
ZRB2313C9358PLA0085
description

-

description

recombinant, expressed in HEK 293 cells

description

~2 mg/mL, clone DCS-310, purified from hybridoma cell culture

description

Powered by Bethyl Laboratories, Inc.

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

species reactivity

human

species reactivity

human, mouse

species reactivity

human

species reactivity

human

biological source

goat

biological source

rabbit

biological source

mouse

biological source

rabbit

clone

polyclonal

clone

2E14, recombinant monoclonal

clone

DCS-310, monoclonal

clone

polyclonal

antibody form

affinity purified immunoglobulin

antibody form

purified antibody

antibody form

purified from hybridoma cell culture

antibody form

affinity purified immunoglobulin

technique(s)

western blot: 1:2,500- 1:15,000

technique(s)

western blot: suitable, immunohistochemistry: suitable, immunocytochemistry: suitable

technique(s)

microarray: suitable, western blot: 1-2 μg/mL using whole extract of cultured 293T (human embryonal kidney) cells, immunoprecipitation (IP): suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

technique(s)

western blot: 1:1,000-1:5,000, immunoprecipitation (IP): 2-10 μg/mg, immunohistochemistry: 1:1,000- 1:5,000


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Storage Class

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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