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Anti-PDL-1 antibody produced in rabbit

Name: Anti-PDL-1 antibody produced in rabbit
Brand: SIGMA
Price: 580 USD
Availability: InStock

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-B7-H1, Anti-CD274 molecule, Anti-Cardif, Anti-IPS-1, Anti-Programmed cell death 1 ligand-1

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Size/SKU	Availability	Price
100 μg	Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)	$580.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), FACS, IF, IHC, WB

Citations:

$580.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

A recombinant, preservative-free antibody is available for your target. Try ZRB1026

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 32 kDa

species reactivity

human, rat, mouse

technique(s)

flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

UniProt accession no.

Q9NZQ7

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CD274(29126)

Description

General description

PDL-1 (programmed cell death 1 ligand 1) is a cell surface protein, that is also known as B7-H1 (B7 homolog 1), coded by CD274 (cluster of differentiation 274) gene. It is located on chromosome 9p24.1. It is present on placental cells, vascular endothelial cells, liver cells, epithelial cells, mesenchymal stem cells, B cells, T cells, dendritic cells and macrophages. It is also expressed in various tumor types like melanoma, glioblastoma, cancers in the lung, kidney, head, neck, stomach, colon, pancreas, breast, cervix and ovary.

Immunogen

17 amino acid peptide from near the center of human PDL-1.

Biochem/physiol Actions

PDL-1 (programmed cell death 1 ligand 1) helps to clear sudden HPV (human papilloma virus) infections. It prevents the multiplication and adherence of T-cell and production of cytokine. It also controls the activities of T-cells in peripheral tissues.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Other Notes

The action of this antibody can be blocked using blocking peptide SBP4059.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB2500216	MABC980	MABC290
Sigma-Aldrich PRS4059 Anti-PDL-1 antibody produced in rabbit	Sigma-Aldrich SAB2500216 Anti-CD274/PD-L1 antibody produced in goat	Sigma-Aldrich MABC980 Anti-PD-L1 Antibody, clone 29E.2A3.C6, Azide Free	Sigma-Aldrich MABC290 Anti-PDL-1/CD274 Antibody, clone 3F2.1
description affinity isolated antibody, buffered aqueous solution	description affinity isolated antibody, buffered aqueous solution	description clone 29E.2A3.C6, from mouse	description clone 3F2.1, 1 mg/mL, from mouse
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form purified immunoglobulin
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source goat	biological source mouse	biological source mouse
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
technique(s) flow cytometry: suitable, immunohistochemistry: suitable, western blot: suitable, immunofluorescence: suitable, indirect ELISA: suitable	technique(s) flow cytometry: suitable, immunofluorescence: suitable, indirect ELISA: suitable, western blot: suitable	technique(s) flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin), neutralization: suitable	technique(s) immunohistochemistry: suitable, western blot: suitable
clone polyclonal	clone polyclonal	clone 29E.2A3.C6, monoclonal	clone 3F2.1, monoclonal

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c