A customer's feedback utlizing the method outlined in Moroi, M. et al., Blood, 88(6), 2081-2092 (1996), stated it performed pretty well, giving a strong green signal using a standard GFP-filter.
Q2876
Quinacrine mustard dihydrochloride
≥85% (HPLC)
Synonym(s):
2-Methoxy-6-chloro-9-(4-bis[β-chloroethyl]amino-1-methylbutylamino)acridine dihydrochloride, 9-[4-(Bis(2-chloroethyl)amino)-1-methylbutylamino]-6-chloro-2-methoxyacridine dihydrochloride
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| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Check Cart for Availability | $318.00 |
About This Item
Empirical Formula (Hill Notation):
C23H28Cl3N3O · 2HCl
CAS Number:
Molecular Weight:
541.77
UNSPSC Code:
12352101
NACRES:
NA.32
PubChem Substance ID:
EC Number:
224-140-9
Beilstein/REAXYS Number:
3819822
MDL number:
Quality Segment
assay
≥85% (HPLC)
storage temp.
−20°C
SMILES string
Cl[H].Cl[H].COc1ccc2nc3cc(Cl)ccc3c(NC(C)CCCN(CCCl)CCCl)c2c1
InChI
1S/C23H28Cl3N3O.2ClH/c1-16(4-3-11-29(12-9-24)13-10-25)27-23-19-7-5-17(26)14-22(19)28-21-8-6-18(30-2)15-20(21)23;;/h5-8,14-16H,3-4,9-13H2,1-2H3,(H,27,28);2*1H
InChI key
JETDZFFCRPFPDH-UHFFFAOYSA-N
General description
Quinacrine mustard dihydrochloride is a fluorescent acridine dye, also abbreviated as QM. In an aqueous solution, the chloroethyl groups rapidly lose chloride ions yielding aziridinium cations. These readily react with the carboxyl, thiol, and heterocyclic ring nitrogen groups of proteins and nucleic acids, or with other nucleophiles.
Application
Quinacrine mustard dihydrochloride is used to stain metaphase chromosomes. Recent applications include the Q-banding of maize and karyotyping of fish. The dye is also used as a vital stain for trypanosomes.
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This Item | |||
|---|---|---|---|
| description ≥85% (HPLC) | description ≥90% | description A non-specific phospholipase A2 (PLA2) inhibitor. | description >97% (GC), powder |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| assay ≥85% (HPLC) | assay ≥90% | assay ≥98% (HPLC) | assay >97% (GC) |
| storage temp. −20°C | storage temp. - | storage temp. 10-30°C | storage temp. −20°C |
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Is quinacrine mustard, product Q2876, suitable as a viability stain for platelets?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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