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R2028

RHC 80267

≥98% (HPLC), solid

Synonym(s):

1,6-bis(Cyclohexyloximinocarbonylamino)hexane, U 57908

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAY

$96.30
25 mg

Estimated to ship onOctober 16, 2026fromMILWAUKEE

$540.00

About This Item

Empirical Formula (Hill Notation):
C20H34N4O4
CAS Number:
Molecular Weight:
394.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106300
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$96.30


Available to ship TODAYDetails


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Quality Segment

assay

≥98% (HPLC)

form

solid

color

white

solubility

DMSO: 9 mg/mL

SMILES string

O=C(NCCCCCCNC(=O)O\N=C1/CCCCC1)O\N=C2/CCCCC2

InChI

1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26)

InChI key

RXSVYGIGWRDVQC-UHFFFAOYSA-N

Biochem/physiol Actions

RHC 80267 is a diacylglycerol (DAG) lipase inhibitor and an important second messenger in signal transduction pathways. RHC 80267 is generated by the hydrolysis of phosphatidylinositol (PI) and bPC by phospholipase C (PLC). DAG mediates the actions of a large number of hormones and cytokines by activating protein kinase C (PKC). A sustained elevation in intracellular DAG may cause neoplastic transformation.
RHC 80267 is a diacylglycerol (DAG) lipase inhibitor.

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This Item
554994266785SML3270
description

≥98% (HPLC), solid

description

Selective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells.

description

The Diacylglycerol Kinase Inhibitor I, also referenced under CAS 93076-89-2, controls the biological activity of Diacylglycerol Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

description

≥98% (HPLC)

form

solid

form

solid

form

solid

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

DMSO: 9 mg/mL

solubility

ethanol: 25 mg/mL, DMSO: 25 mg/mL

solubility

DMSO: 4 mg/mL, ethanol: 12 mg/mL

solubility

DMSO: 2 mg/mL, clear

color

white

color

white to off-white

color

white

color

white to beige


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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