R3250 is classified as a matrix dispersion. This product contains gelatin, sugar, modified food starch, and other components to make it convenient as an "oil dispersible material," which will not dissolve in chloroform. The gelatin and starch components in this product would not be soluble but will be dispersed or suspended in the oil. For a soluble retinol acetate product, recommended Product No. is R4632, Retinol Acetate all trans, which is soluble in chloroform (50 mg/ml), yielding a clear, yellow-green solution. Product No. R4632 is also soluble in ethanol.
R3250
Retinyl acetate
synthetic, matrix dispersion, 475,000-650,000 USP units/g
Synonym(s):
Retinol acetate, Vitamin A acetate
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| Size/SKU | Availability | Price |
|---|---|---|
10 g | Available to ship TODAYfromMILWAUKEE | $31.50 $149.00 |
100 g | Available to ship TODAYfromMILWAUKEE | $149.00 |
About This Item
Empirical Formula (Hill Notation):
C22H32O2
CAS Number:
Molecular Weight:
328.49
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058009
UNSPSC Code:
12352205
EC Number:
204-844-2
MDL number:
Beilstein/REAXYS Number:
1915439
biological source
synthetic
Quality Segment
form
matrix dispersion
specific activity
475,000-650,000 USP units/g
color
yellow
mp
57-58 °C
storage temp.
−20°C
SMILES string
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
InChI
1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
InChI key
QGNJRVVDBSJHIZ-QHLGVNSISA-N
General description
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate.
Application
Retinyl acetate has been used:
- a control diet to study its effect at different developmental periods in fish larvae
- to study its inhibitory effects on Mycobacterium avium subspecies paratuberculosis (MAP) strains
- as an internal standard in high performance liquid chromatography (HPLC) to quantify vitamin A in fortified milk
Biochem/physiol Actions
Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as required. Retinyl acetate is used in a wide range of biological applications. It acts as a chemopreventive agent. Retinyl acetate also has antineoplastic property.
Physical form
Dispersion in cornstarch-gelatin matrix. Oil dispersible
Analysis Note
Activity based on HPLC comparison to USP standard.
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This Item | |||
|---|---|---|---|
| description synthetic, matrix dispersion, 475,000-650,000 USP units/g | description analytical standard | description European Pharmacopoeia (EP) Reference Standard | description Pharmaceutical Secondary Standard; Certified Reference Material |
| biological source synthetic | biological source - | biological source synthetic | biological source - |
| form matrix dispersion | form - | form solid | form - |
| storage temp. −20°C | storage temp. -10 to -25°C | storage temp. −20°C | storage temp. 2-8°C |
| mp 57-58 °C | mp 57-58 °C | mp 57-58 °C | mp 57-58 °C |
| color yellow | color - | color - | color - |
| Quality Level 200 | Quality Level 100 | Quality Level - | Quality Level 300 |
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signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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What is the solubility information for this product? It is not dissolved in hexane, heptane, acetone, isopropyl alcohol, water, and absolute ethanol; even left overnight on stir plate.
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