R8626
Rifamycin SV sodium salt
potency: ≥ 900 IU/mg (anhydrous basis)
Synonym(s):
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl- 21-acetate monosodium salt, Rifamycin SV monosodium salt
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About This Item
form
powder
Quality Segment
potency
≥ 900 IU/mg (anhydrous basis)
solubility
ethanol: soluble 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycobacteria
mode of action
protein synthesis | interferes
SMILES string
[Na+].CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)cc([O-])c4c3C2=O
InChI
1S/C37H47NO12.Na/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41;/h10-16,18-20,25,29-30,33,40-44H,1-9H3,(H,38,46);/q;+1/p-1/b11-10+,14-13+,17-12-;/t16-,18+,19+,20+,25-,29-,30+,33+,37-;/m0./s1
InChI key
YVOFSHPIJOYKSH-NLYBMVFSSA-M
General description
Application
Biochem/physiol Actions
Packaging
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| description potency: ≥ 900 IU/mg (anhydrous basis) | description - | description Pharmaceutical Secondary Standard; Certified Reference Material | description potency: 916-964 μg per mg |
| mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action - | mode of action cell wall synthesis | interferes |
| antibiotic activity spectrum Gram-negative bacteria, mycobacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
| form powder | form powder | form - | form powder |
| potency ≥ 900 IU/mg (anhydrous basis) | potency ≥4100 I.U. per mg (dry basis) | potency - | potency 916-964 μg per mg |
| solubility ethanol: soluble 50 mg/mL | solubility methanol: soluble | solubility - | solubility H2O: 50 mg/mL |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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