Skip to Content
MilliporeSigma

Skip To

R8900

Ro 8-4304

solid

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg
Check Cart for Availability
$148.00

About This Item

Empirical Formula (Hill Notation):
C21H23FN2O3 · HCl
Molecular Weight:
406.88
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Form:
solid

$148.00


Check Cart for Availability

​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


form

solid

Quality Segment

solubility

H2O: ≤0.5 mg/mL

originator

Roche

storage temp.

2-8°C

SMILES string

Cl.NC(=O)c1ccc(OCCC(O)N2CCC(=CC2)c3ccc(F)cc3)cc1

InChI

1S/C21H23FN2O3.ClH/c22-18-5-1-15(2-6-18)16-9-12-24(13-10-16)20(25)11-14-27-19-7-3-17(4-8-19)21(23)26;/h1-9,20,25H,10-14H2,(H2,23,26);1H

InChI key

NYFXHCMXYODFLP-UHFFFAOYSA-N

Gene Information

human ... GRIN2B(2904)

Biochem/physiol Actions

NR2B-selective, noncompetitive NMDA glutamate receptor antagonist

Features and Benefits

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
R108I117I0157
description

solid

description

solid

description

≥98% (HPLC), solid

description

≥99% (HPLC), solid

form

solid

form

solid

form

solid

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: ≤0.5 mg/mL

solubility

H2O: slightly soluble <0.7 mg/mL, ethanol: soluble, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.0 mg/mL

solubility

ethanol: 20 mg/mL, H2O: 0.2 mg/mL, dilute aqueous acid: insoluble, 0.1 M NaOH: 2.8 mg/mL, DMSO: >20 mg/mL

solubility

H2O: soluble 4.5 mg/mL, DMSO: soluble 28 mg/mL

originator

Roche

originator

-

originator

-

originator

-

Gene Information

human ... GRIN2B(2904)

Gene Information

human ... COMT(1312)

Gene Information

-

Gene Information

human ... PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144)


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters