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RAB0161

Phospho-EGFR (pSer1070) ELISA Kit

for detection of human, mouse or rat phospho-egfr (pSer1070) in cell and tissue lysates

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1 kit
Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)
$769.00

About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... EGFR(1965)
Input:
sample type tissue lysate
sample type cell lysate
Species reactivity:
mouse, human, rat
Storage temp.:
−20°C
Shipped in:
wet ice

$769.00

Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)
​
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species reactivity

mouse, human, rat

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type tissue lysate
sample type cell lysate

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... EGFR(1965)

General description

The Human BLC ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human BLC in serum, plasma, cell culture supernatants and urine.
The EGFR (epidermal growth factor receptor) family includes four receptor tyrosine kinases, EGF R (ErbB1), ErbB2 (neu), ErbB3, and ErbB4. EGF R is present on many cell types of epithelial and mesenchymal lineages. The gene EGFR is mapped to human chromosome 7p11.2.

Immunogen

EGFR (pTyr1070) synthetic phosphopeptide

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

The members of epidermal growth factor receptor (EGF R) or the ErbB receptor family have been identified as useful biomarkers and targets for cancer therapy. EGF R binds EGF and induces tyrosine phosphorylation leading to proliferation of cells. EGF R is capable of binding transforming growth factor-α and heparin-binding EGF in addition to EGF. There are numerous effector molecules activated by EGF R that result in a variety of biological processes such as morphogenesis, cell motility, apoptosis, differentiation and organ repair and maintenance. Deregulation of EGF R signaling is implicated in progression of a wide variety of tumors, invasion and metastasis. Phosphorylation of Tyr1068 occurs by autophosphorylation of EGF R and is required for the binding of Grb2 (Growth factor receptor-bound protein 2) and activation of ERK1/2 (extracellular signal-regulated kinases) pathway.

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RAB0165RAB0167RAB0160
Phospho-EGFR (pSer1070) ELISA Kit for detection of human, mouse or rat phospho-egfr (pSer1070) in cell and tissue lysates

Sigma-Aldrich

RAB0161

Phospho-EGFR (pSer1070) ELISA Kit

Phospho-EGFR (pTyr1068) ELISA Kit for detection of human phospho-egfr (pTyr1068) in cell and tissue lysates

Sigma-Aldrich

RAB0165

Phospho-EGFR (pTyr1068) ELISA Kit

Phospho-EGFR (pTyr1086) ELISA Kit for detection of human phospho-egfr (pTyr1086) in cell and tissue lysates

Sigma-Aldrich

RAB0167

Phospho-EGFR (pTyr1086) ELISA Kit

Human EGFR / ErbB1 ELISA Kit for serum, plasma, cell culture supernatants and urine

Sigma-Aldrich

RAB0160

Human EGFR / ErbB1 ELISA Kit

description

for detection of human, mouse or rat phospho-egfr (pSer1070) in cell and tissue lysates

description

for detection of human phospho-egfr (pTyr1068) in cell and tissue lysates

description

for detection of human phospho-egfr (pTyr1086) in cell and tissue lysates

description

for serum, plasma, cell culture supernatants and urine

Gene Information

human ... EGFR(1965)

Gene Information

human ... EGFR(1965)

Gene Information

human ... EGFR(1965)

Gene Information

human ... EGFR(1965)

species reactivity

mouse, human, rat

species reactivity

human

species reactivity

human

species reactivity

human

input

sample type tissue lysate
sample type cell lysate

input

sample type: human tissue lysate
sample type: human cell lysate

input

sample type: human cell lysate
sample type: human tissue lysate

input

sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

flash_point_f

Not applicable

flash_point_c

Not applicable

Hazard Classifications

Met. Corr. 1

Storage Class

12 - Non Combustible Liquids

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