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RAB1050

Human Galectin-8 ELISA Kit

for cell culture supernatants, plasma, and serum samples

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96 wells
Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)
$622.00

About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... LGALS8(3964)
Input:
sample type plasma
sample type serum sample(s)
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice

$622.00


Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)

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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type serum sample(s)
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.16 ng/ml

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... LGALS8(3964)

General description

This ELISA antibody pair detects Human Galectin-8 (LGALS8)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

Galectin-8 (Gal-8) is a member of “tandem-repeat” galectin family, possesses two carbohydrate binding domains linked by a short peptide. The short peptide accounts for Gal-8 cell adhesion and downstream signalling. Tumor cells, as well as normal tissues, express Gal-8. The expression level of Gal-8 is higher in multiple myeloma conditions and enhances adhesion to vascular endothelium. Galectin-8 binds to integrin selectively and inhibits cell adhesion and promotes apoptosis. Gal-8 interacts with integrin alpha and regulates neutrophil adhesion to endothelial cells and migration. Gal-8 ligand binds to cluster of differentiation 44 (CD44) and causes an inflammatory response in rheumatoid arthritis. Overexpression of Gal-8 plays a key role in metastasis of prostate cancer and cell survival by causing rearrangement of the cytoskeleton and E-cadherin expression.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

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This Item
RAB0337RAB1143RAB1901
description

for cell culture supernatants, plasma, and serum samples

description

for serum, plasma, cell culture supernatants and urine

description

for cell culture supernatants, plasma, and serum samples

description

for serum, plasma and cell culture supernatants

Gene Information

human ... LGALS8(3964)

Gene Information

human ... LGALS7(3963)

Gene Information

rat ... Lgals3(83781)

Gene Information

rat ... Lgals1(56646)

species reactivity

human

species reactivity

human

species reactivity

mouse, rat

species reactivity

rat

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.16 ng/ml

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 13.72-10000 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 3 pg/ml

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.15 ng/mL
standard curve range: 0.102-25 ng/mL

input

sample type plasma
sample type serum sample(s)
sample type cell culture supernatant(s)

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine

input

sample type plasma
sample type serum sample(s)
sample type cell culture supernatant(s)

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable


pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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