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Mouse EPO ELISA Kit

Name: Mouse EPO ELISA Kit
Brand: SIGMA
Price: 716 USD

for cell culture supernatants, plasma, and serum samples

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Pack Size	SKU	Availability	Price
96 wells		Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)	$716.00

About This Item

NACRES:

NA.32

UNSPSC Code:

41116158

Gene information:

mouse ... Epo(13856)

Input:

sample type cell culture supernatant(s)
sample type plasma
sample type serum sample(s)

Species reactivity:

mouse

Storage temp.:

−20°C

Shipped in:

wet ice

$716.00

Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)

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Properties

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum sample(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 pg/ml

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Epo(13856)

Description

General description

This ELISA antibody pair detects Mouse Erythropoietin (EPO)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

Erythropoietin (EPO) is a glycoprotein hormone which is essential for the proliferation of erythropoietic progenitors to produce red blood cells (RBCs). Peritubular fibroblast in kidney cortex is the primary site for EPO production in adults, though spleen, bone marrow and liver contribute to the production. In fetus, liver is the primary site for EPO production. Additionally, EPO functions in some cytoprotective activities like, antiapoptotic, antioxidant, and anti-inflammatory responses. Hypoxia inducible factors upregulate EPO expression. EPO expression increases with decreased hemoglobin concentration in few cases of anemia. Decreased production of EPO is the cause of anemia in chronic kidney diseases. Circulating endogenous antibodies to EPO (anti-EPO) is the cause of anemia in multiple diseases like human immunodeficiency virus (HIV) infection, hepatitis C virus infection, systemic lupus erythematosus. Gain-of-function polymorphism in EPO causes familial erythrocytosis.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

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This Item	RAB0559	RAB1177	RAB1858
Sigma-Aldrich RAB1122 Mouse EPO ELISA Kit	Sigma-Aldrich RAB0559 Mouse Fcgr2b ELISA Kit	Sigma-Aldrich RAB1177 Mouse TSP-2 ELISA Kit	Sigma-Aldrich RAB1858 Mouse PDGF-BB ELISA
Gene Information mouse ... Epo(13856)	Gene Information mouse ... Fcgr2b(14130)	Gene Information mouse ... Thbs2(21826)	Gene Information mouse ... Pdgfrb(18596)
species reactivity mouse	species reactivity mouse	species reactivity mouse	species reactivity mouse
assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 1.5 pg/ml	assay range inter-assay cv: <10% intra-assay cv: <12% sensitivity: 80 pg/mL	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.16 ng/ml	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 24 pg/mL standard curve range: 24.6-6000 pg/mL
input sample type cell culture supernatant(s) sample type plasma sample type serum sample(s)	input sample type cell culture supernatant(s) sample type serum sample type plasma	input sample type serum sample(s) sample type plasma sample type cell culture supernatant(s)	input sample type plasma sample type serum sample type cell culture supernatant(s)
technique(s) ELISA: suitable	technique(s) ELISA: suitable	technique(s) ELISA: suitable	technique(s) ELISA: suitable
detection method colorimetric	detection method colorimetric	detection method colorimetric	detection method colorimetric