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RAB1127

Mouse PAI-1 ELISA Kit

for cell culture supernatants, plasma, and serum samples

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1 kit
Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)
$737.00

About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Species reactivity:
mouse, human
Storage temp.:
−20°C
Shipped in:
wet ice

$737.00


Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)

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species reactivity

mouse, human

technique(s)

ELISA: suitable

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/ml

shipped in

wet ice

storage temp.

−20°C

General description

This ELISA antibody pair detects mouse and human PAI-1.
The PAI-1 (plasminogen activator inhibitor) gene is localized to human chromosome 7q22.1. Active form of PAI-1 is expressed in the blood and tissues. Platelets harbor both the active and latent forms of PAI-1.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

PAI-1 (plasminogen activator inhibitor) produced by platelets takes part in stabilizing blood clotting mechanism. PAI-1 prevents plasminogen activation during fibrinolysis. This might lead to the risk of cardiovascular disease. Elevated levels of PAI-1 has been observed in type 2 diabetes mellitus and serves the reason for reduced insulin sensitivity. PAI-1 stimulates the process of cellular senescence. PAI-1 regulation occurs through p53 dependent TGF-β (transforming growth factor-β) signalling. Studies also also predict that stress and depression might influence PAI-1 expression.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

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description

for cell culture supernatants, plasma, and serum samples

description

for cell culture supernatants, plasma, and serum samples

description

for cell culture supernatants, plasma, and serum samples

description

for serum, plasma and cell culture supernatants

species reactivity

mouse, human

species reactivity

mouse, human, rhesus monkey

species reactivity

mouse

species reactivity

mouse

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/ml

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/ml

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 pg/ml

assay range

inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 6 pg/mL

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

10 - Combustible liquids



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