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S0577

Streptokinase C from Streptococcus sp.

lyophilized solid, ≥3,500 unit/mg solid

Synonym(s):

Streptokinase

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Size/SKUAvailabilityPrice
10000 units
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$54.80
50000 units
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$155.00

About This Item

UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
Specific activity:
≥3,500 unit/mg solid
Assay:
40—60% protein (biuret)
Biological source:
bacterial (Streptococcus sp.)
Recombinant:
expressed in E. coli

$54.80


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biological source

bacterial (Streptococcus sp.)

Quality Segment

recombinant

expressed in E. coli

assay

40—60% protein (biuret)

form

lyophilized solid

specific activity

≥3,500 unit/mg solid

color

off-white to light yellow

application(s)

life science and biopharma

storage temp.

−20°C

Gene Information

Streptococcus pyogenes ... SKC(134997)

General description

Research area: Cell Signaling

Streptokinase is an extracellular enzyme, a single-chain polypeptide produced by several strains of β-hemolytic Streptococci. It is composed of multiple structural domains like α-, β-, and γ-domains that are involved in various functions.

Application

Streptokinase C from Streptococcus sp. has been used to quantitate the survival of Staphylococcus aureus in whole human blood.

Biochem/physiol Actions

Streptokinase shows fibrinolytic activity by triggering the circulatory plasminogen either via a fibrin-dependent or fibrin-independent mechanism. Streptokinase has been studied majorly in terms of its therapeutic efficacy and treating myocardial infarction to dissolve clots.

Physical form

Lyophilized powder containing approx. 50% bovine serum albumin (total protein by biuret) with sodium glutamate.

Other Notes

One unit will liquify a standard clot of fibrinogen, plasminogen, and thrombin at pH 7.5 at 37 °C in 10 min.

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This Item
S5265Y0000868S3134
description

lyophilized solid, ≥3,500 unit/mg solid

description

lyophilized powder, Protein ~3 % by Lowry, 25,000-50,000 U/vial

description

European Pharmacopoeia (EP) Reference Standard

description

lyophilized powder, ≥2,000 units/mg solid

biological source

bacterial (Streptococcus sp.)

biological source

-

biological source

-

biological source

-

assay

40—60% protein (biuret)

assay

-

assay

-

assay

-

specific activity

≥3,500 unit/mg solid

specific activity

25,000-50,000 U/vial

specific activity

-

specific activity

≥2,000 units/mg solid

Gene Information

Streptococcus pyogenes ... SKC(134997)

Gene Information

Streptococcus pyogenes MGAS8232 ... slo(993428)

Gene Information

-

Gene Information

-

application(s)

life science and biopharma

application(s)

-

application(s)

pharmaceutical
pharmaceutical (small molecule)

application(s)

-

form

lyophilized solid

form

lyophilized powder

form

-

form

lyophilized powder


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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