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S0697

Anti-Sortilin antibody produced in rabbit

lyophilized powder, affinity isolated antibody

Synonym(s):

Anti-SORT1

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Pack SizeSKUAvailabilityPrice
50 μL
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$549.00
200 μL
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$1,150.00

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
4

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biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse, rat, human

technique(s)

immunohistochemistry: suitable, western blot: 1:200 using rat brain lysates

UniProt accession no.

Q99523

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SORT1(6272)
mouse ... Sort1(20661)
rat ... Sort1(83576)

General description

Sortilin is neurotensin receptor 3 (NTS3), one of the receptors for the peptide neurotransmitter neurotensin that exerts several biological functions ranging from the regulation of dopamine transmission and pain in the central nervous system to its functioning as a local hormone affecting the gastrointestinal tract. Sortilin expression was found to be essential for proNGF and proBDNF-induced neuronal cell death

Immunogen

peptide DKDTTRRIHVSTDQD(C) corresponding to residues 320-335 of human sortilin.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide.

Preparation Note

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

form

lyophilized powder

form

buffered aqueous solution

form

lyophilized powder

form

buffered aqueous solution

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Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000434497
0000434497
0000337988
0000337988
SLCB7240

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Related Content

Data Sheet - S0697

Instructions

Margalida Cifre et al.
Molecular neurodegeneration, 13(1), 14-14 (2018-03-24)
Metabolically-obese, normal-weight (MONW) individuals are not obese in terms of weight and height but have a number of obesity-related features (e.g. greater visceral adiposity, insulin resistance, and increased risk of cardiovascular disease). The MONW phenotype is related to the intake
Gregory T Jones et al.
Human molecular genetics, 22(14), 2941-2947 (2013-03-29)
Abdominal aortic aneurysm (AAA) is a common human disease with a high estimated heritability (0.7); however, only a small number of associated genetic loci have been reported to date. In contrast, over 100 loci have now been reproducibly associated with
Idy H T Ho et al.
Theranostics, 9(6), 1651-1665 (2019-05-01)
Rationale: Brain-derived neurotrophic factor (BDNF) is a key mediator in the development of chronic pain. Sortilin is known to interact with proBDNF and regulate its activity-dependent secretion in cortical neurons. In a rat model of inflammatory pain with intraplantar injection
View All Related Papers

Global Trade Item Number

SKUGTIN
S0697-200UL04061838173973
S0697-50UL04061838032973

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