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S1940

Anti-phospho-Src (pTyr418) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Synonym(e):

Anti-pp60src(pY418)

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PackungsgrößeSKUVerfügbarkeitPreis
1 vial
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€ 710,00

Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.44
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
7

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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

chicken, mouse, human, rat

technique(s)

western blot: 1:1,000 using human platelets or mouse NIH3T3 cells

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr418)

Gene Information

human ... SRC(6714)
mouse ... Src(20779)
rat ... Src(83805)

General description

Src is a proto-oncogene that regulates neuronal functions, such as nerve cell differentiation. The Src kinase family structurally comprises of SH2, SH3 and kinase domains, as well as a negative regulatory C-terminal tail. Src has also been implicated in functions such as cell growth, development and cell-cell interactions . Anti-phospho-Src p(Tyr418) antibody is specific for human, mouse, rat and chicken Src (60 kDa).

Immunogen

The sequence is conserved in human, mouse, chicken and frog.
synthetic phosphopeptide derived from the region of src that contains tyrosine 418, based on the sequence of human src.

Application

Anti-phospho-Src p(Tyr418) antibody is suitable for use in western blot (1:1,000 using human platelets or mouse NIH3T3 cells). The product may also be used for immunoprecipitation (1:1000 using HEK293 or HEL cell lysates ).

Physical form

Solution in Dulbecco′s phosphate-buffered saline (without Mg2+ and Ca2+), pH 7.3, with 50% glycerol, 1.0 mg/ml BSA (IgG and protease free) and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel
SAB5700365SAB2103351SAB5700336
Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

conjugate

-

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


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Lagerklasse

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Verwandter Inhalt


C A Ingraham et al.
Molecular and chemical neuropathology, 10(1), 1-14 (1989-02-01)
The proto-oncogene c-src has been implicated in the development and mature function of the nervous system. pp60c-src, the protein product of the c-src gene, is a tyrosine protein kinase that is highly enriched in fetal neural tissue. pp60c-src appears in
Xiaoming Fan et al.
International journal of molecular sciences, 19(7) (2018-07-25)
Non-coding RNAs are important regulators of protein-coding genes. The current study characterized an antisense long non-coding RNA, ATP1A1-AS1, which is located on the opposite strand of the Na/K-ATPase α1 gene. Our results show that four splice variants are expressed in
J R Engen et al.
Cellular and molecular life sciences : CMLS, 65(19), 3058-3073 (2008-06-20)
Src-family kinases are modular signaling proteins involved in a diverse array of cellular processes. All members of the Src family share the same domain organization, with modular SH3, SH2 and kinase domains followed by a C-terminal negative regulatory tail. X-ray



Global Trade Item Number

SKUGTIN
S1940-1VL04061826592748

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