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S3065

SC 19220

≥98% (HPLC), solid

Synonym(s):

2-Acetylhydrazide 10(11H)-carboxylic acid, 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid

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Size/SKUAvailabilityPrice
10 mg

Estimated to ship TODAY

$200.00

About This Item

Empirical Formula (Hill Notation):
C16H14N3O3Cl
CAS Number:
Molecular Weight:
331.75
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$200.00


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Quality Segment

assay

≥98% (HPLC)

form

solid

color

white

mp

190-191 °C (lit.)

solubility

DMSO: soluble 10 mg/mL, H2O: insoluble

SMILES string

CC(=O)NNC(=O)N1Cc2ccccc2Oc3ccc(Cl)cc13

InChI

1S/C16H14ClN3O3/c1-10(21)18-19-16(22)20-9-11-4-2-3-5-14(11)23-15-7-6-12(17)8-13(15)20/h2-8H,9H2,1H3,(H,18,21)(H,19,22)

InChI key

KNURFLJTOUGOOQ-UHFFFAOYSA-N

Gene Information

human ... PTGER1(5731)
rat ... Ptger1(25637)

Application

SC 19220 was used to study the role of prostaglandin E2 in oxygen-glucose deprivation-induced neurotoxicity and preconditioning-induced neuroprotection in rat cortical cultures.

Biochem/physiol Actions

SC 19220 is a competitive antagonist of prostaglandin E receptors. It competes with PGE2 in regulating vesicourethral motility and increases the bladder capacity of rats. It inhibits the contraction of smooth muscles in response to prostaglandins E2 and F2α. SC 19220 also inhibits the formation of osteoclasts induced by vitamin D3, parathyroid hormone, IL-11 and IL-6.
EP1 Prostanoid receptor antagonist

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vibrant-m

SC 11

description

≥98% (HPLC), solid

description

targeting mouse Ptgfr

description

≥95% (HPLC)

description

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA.

form

solid

form

lyophilized powder

form

powder

form

-

assay

≥98% (HPLC)

assay

-

assay

≥95% (HPLC)

assay

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

solubility

H2O: insoluble, DMSO: soluble 10 mg/mL

solubility

-

solubility

DMSO: 2 mg/mL, clear

solubility

-

color

white

color

-

color

white to beige

color

-

Gene Information

human ... PTGER1(5731)
rat ... Ptger1(25637)

Gene Information

mouse ... PTGFR(19220), Ptgfr(19220)

Gene Information

-

Gene Information

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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