S4264
Spermine
suitable for cell culture, BioReagent
Synonym(s):
N,N′-Bis(3-aminopropyl)-1,4-diaminobutane, Gerontine, Musculamine, Neuridine
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 g | Available to ship TODAYfromMILWAUKEE | $98.60 |
5 g | Available to ship TODAYfromMILWAUKEE | $327.00 |
About This Item
Quality Segment
biological source
microbial, synthetic
product line
BioReagent
assay
≥96%
form
semisolid
technique(s)
cell culture | mammalian: suitable
bp
150 °C/5 mmHg (lit.)
mp
28-30 (lit.)
solubility
H2O: 50 mg/mL
storage temp.
2-8°C
SMILES string
[H]N(CCCN)CCCCN([H])CCCN
InChI
1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2
InChI key
PFNFFQXMRSDOHW-UHFFFAOYSA-N
Gene Information
human ... GRIN2B(2904)
rat ... Grin2a(24409)
Application
- in the buffer, to swap the divalent cations in the MgSO4 protocol to stabilize the integrity of the chromosomes
- in the preparation of modified mica surfaces from freshly cleaved mica surfaces
- to study its effects on survival in mice with sepsis and to estimate the role of spermine in lethal systemic inflammatory diseases
Biochem/physiol Actions
Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
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This Item | |||
|---|---|---|---|
| description suitable for cell culture, BioReagent | description ≥97% | description ≥99.0% (GC) | description analytical standard |
| biological source synthetic, microbial | biological source synthetic, microbial | biological source microbial, synthetic | biological source - |
| assay ≥96% | assay ≥97% | assay ≥99.0% (GC) | assay ≥99.0% (GC), 97.0-103.0% (T) |
| Gene Information human ... GRIN2B(2904) | Gene Information human ... GRIN2B(2904) | Gene Information - | Gene Information - |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| form semisolid | form - | form crystalline (chunks) | form - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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