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S6311

Anti-phospho-S6-Kinase (pThr389) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-phospho-p70S6K (pThr389)

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0.1 mL
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$906.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.44
MDL number:
MFCD02097170
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB CL
Citations:
8

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biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

mouse, rat, human

technique(s)

western blot (chemiluminescent): 1:1,000 using serum-treated NIH3T3 cell extract, or insulin-treated HeLa, COS, and C6 cell extracts

UniProt accession no.

P23443

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer389)

Gene Information

human ... RPS6KB1(6198)
mouse ... Rps6kb1(72508)
rat ... Rps6kb1(83840)

General description

p70 S6 kinase or p70S6K is a protein that belongs to Ser/Thr protein kinase family. It has a crucial role in cell growth and G1 cell cycle progression. It also has a pivotal role in phosphorylating eEF2k at a conserved serine residue and hence regulating the protein synthesis. Rabbit anti-phospho-(p70S6K) antibody can identify p70 S6 kinase and p85 S6 kinase when phosphorylated at (Thr389). Anti-phospho-S6-kinase (pThr389) antibody reacts specifically with p70 S6 kinase of rat, mouse and human. This product can also detect few phosphorylated isoforms of Protein Kinase C when present at high level in cells.

Immunogen

A synthetic phospho-(Thr389) peptide corresponding to residues around (Thr389) of human p70 S6 kinase, coupled to KLH.

Application

Anti-phospho-S6-kinase (pThr389) antibody can be used in western blotting (chemiluminescent) (diluted 1:1000) using serum-treated NIH3T3 cell extract or insulin-treated HeLa, COS, and C6 cell extracts.

Physical form

Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-phospho-S6-Kinase (pThr389) antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution

Sigma-Aldrich

S6311

Anti-phospho-S6-Kinase (pThr389) antibody produced in rabbit

Anti-phospho-S6-Kinase (pThr421/pSer424) antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution

Sigma-Aldrich

S6436

Anti-phospho-S6-Kinase (pThr421/pSer424) antibody produced in rabbit

Anti-phospho-p70 S6 Kinase (pThr389/412) antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

SAB4301471

Anti-phospho-p70 S6 Kinase (pThr389/412) antibody produced in rabbit

Anti-p70 S6 Kinase antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

SAB4502684

Anti-p70 S6 Kinase antibody produced in rabbit

description

affinity isolated antibody, buffered aqueous glycerol solution

description

affinity isolated antibody, buffered aqueous glycerol solution

description

affinity isolated antibody

description

affinity isolated antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

-

UniProt accession no.

P23443

UniProt accession no.

P23443

UniProt accession no.

P23443

UniProt accession no.

P23443

species reactivity

mouse, rat, human

species reactivity

mouse, rat, human

species reactivity

human, mouse, rat

species reactivity

rat, human, mouse

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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