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Succinylcholine chloride dihydrate

Name: Succinylcholine chloride dihydrate
Brand: SIGMA
Price: 130 USD
Availability: InStock

98.0-102.0%, Cholinergic antagonist, solid

Synonym(s):

Bis(trimethylammonioethyl) succinate chloride, Succinyldicholine dichloride

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25 g	Available to ship TODAY	$130.00

About This Item

Linear Formula:

[(CH₃)₃NCH₂CH₂OCOCH₂]₂Cl₂ · 2H₂O

CAS Number:

6101-15-1

Molecular Weight:

397.34

NACRES:

NA.77

PubChem Substance ID:

24277873

UNSPSC Code:

41116107

EC Number:

200-747-4

MDL number:

MFCD00150564

Beilstein/REAXYS Number:

3922827

Assay:

98.0-102.0%

Form:

solid

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Properties

Product Name

Succinylcholine chloride dihydrate, 98.0-102.0%, solid

Quality Segment

100

assay

98.0-102.0%

form

solid

color

white

solubility

H₂O: complete 100 mg/ml, clear to slightly hazy, colorless, H₂O: soluble (unstable at pH > 9.)

originator

Novartis

SMILES string

O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C

InChI

1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2

InChI key

FFSBEIRFVXGRPR-UHFFFAOYSA-L

Description

Application

Succinylcholine chloride dehydrate was used to study the mechanism of gating of Cys loop receptors in Xenopus laevis.^4,5

Biochem/physiol Actions

Cholinergic antagonist which induces a long-lasting depolarization of the acetylcholine neuron membrane; neuromuscular blocking agent.

Succinylcholine is a cholinergic antagonist and a neuromuscular blocking agent. It induces depolarization of acetylcholine receptors on the muscle membrane and efflux of potassium from the muscle that leads to hypokalemia in individuals with upregulated expression of acetylcholine receptors.³

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Solutions may be stored for several days at 4 °C.

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This Item	PHR2659	S2200000	1623502
Sigma-Aldrich S8251 Succinylcholine chloride dihydrate	Supelco PHR2659 Succinylcholine Chloride	S2200000 Suxamethonium chloride	USP 1623502 Succinylcholine chloride
description 98.0-102.0%, solid	description Pharmaceutical Secondary Standard; Certified Reference Material	description European Pharmacopoeia (EP) Reference Standard	description United States Pharmacopeia (USP) Reference Standard
assay 98.0-102.0%	assay -	assay -	assay -
form solid	form solid	form -	form -
Quality Level 100	Quality Level 300	Quality Level -	Quality Level -
solubility H₂O: complete 100 mg/ml, clear to slightly hazy, colorless, H₂O: soluble (unstable at pH > 9.)	solubility -	solubility -	solubility -
color white	color -	color -	color -
originator Novartis	originator -	originator -	originator -

Pictograms

GHS06

Signal Word

Danger

Hazard Codes

H301

Precautionary Statements

P301 + P310

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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