S8559
Sinefungin
95% (HPLC), powder, methylation of bases in DNA & RNA inhibitor
Sinônimo(s):
Adenosylornithine, 5′-Deoxy-5′-(1,4-diamino-4-carboxybutyl)adenosine, A-9145, Antibiotic 32232RP
Selecione um tamanho
| Para você/SKU | Disponibilidade | Preço |
|---|---|---|
10 mg | Previsão de entrega em28 de agosto de 2026deCajamar | R$ 6.360,00 |
Sobre este item
Nome do produto
Sinefungin, 95% (HPLC), powder
Quality Segment
assay
95% (HPLC)
form
powder
color
white to yellow
solubility
H2O: complete 20 mg/ml, clear, colorless to light yellow, H2O: soluble
antibiotic activity spectrum
neoplastics
mode of action
DNA synthesis | interferes, enzyme | inhibits
storage temp.
2-8°C
SMILES string
N[C@@H](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23
InChI
1S/C15H23N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h4-8,10-11,14,23-24H,1-3,16-17H2,(H,25,26)(H2,18,19,20)/t6-,7-,8+,10+,11+,14+/m0/s1
InChI key
LMXOHSDXUQEUSF-YECHIGJVSA-N
General description
Application
Biochem/physiol Actions
Methylation inhibition by sinefugin is often accompanied by an altered rate of cytosine deamination that is coupled to transition mutation in the DNA. Sinefugin inhibits Epstein-Barr viral activity and this inhibition is related to the change in DNA methylation and gene expression. It can cause a rate change in several restriction DNA endonuclease activities, including Mme I, which is not connected to the inhibition of the methytransferase activity.
Features and Benefits
1 of 1
Este Item | |||
|---|---|---|---|
| description 95% (HPLC), powder | description ≥99% (HPLC), powder | description Ready Made Solution, from Streptomyces alboniger, 10 mg/mL in H2O, suitable for cell culture | description from Cordyceps militaris |
| form powder | form powder | form ready-to-use solution | form powder |
| assay 95% (HPLC) | assay ≥99% (HPLC) | assay >98% (HPLC) | assay - |
| Quality Level 200 | Quality Level 300 | Quality Level 300 | Quality Level 200 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C |
| solubility H2O: complete 20 mg/ml, clear, colorless to light yellow, H2O: soluble | solubility 0.1 M HCl: 10 mg/mL | solubility H2O: soluble 10 mg/mL | solubility - |
| color white to yellow | color white | color colorless to yellow | color - |
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Classe de armazenamento
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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