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S8689

Fas Ligand, soluble human

recombinant, expressed in HEK 293 cells, lyophilized powder

Synonym(s):

SuperFas Ligand™

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5 μg

Available to ship TODAYfromMILWAUKEE

$954.00
$810.90

About This Item

UNSPSC Code:
12352202
NACRES:
NA.56
MDL number:
Form:
lyophilized powder
Assay:
≥95% (SDS-GE)
Biological source:
human
Recombinant:
expressed in HEK 293 cells
Mol wt:
32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions), 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions)

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biological source

human

Quality Segment

recombinant

expressed in HEK 293 cells

assay

≥95% (SDS-GE)

form

lyophilized powder

mol wt

32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions), 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions)

technique(s)

ligand binding assay: suitable

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... FASLG(356)

Application

ED50 = 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFas Ligand™ recognizes its receptor Fas (CD95) of the following species: human, rat, mouse.

Biochem/physiol Actions

Fas ligand has also been shown to be involved in the activation of non-apoptotic pathways including proliferation and NF-κ B activation.
Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1).

Legal Information

SuperFas Ligand is a trademark of Alexis Biochemicals Corp.

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This Item
SRP8012A9847O2260
description

recombinant, expressed in HEK 293 cells, lyophilized powder

description

recombinant, expressed in HEK 293 cells, >90% (SDS-PAGE)

description

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

description

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

biological source

human

biological source

human

biological source

human

biological source

mouse

assay

≥95% (SDS-GE)

assay

>90% (SDS-PAGE)

assay

>97% (SDS-PAGE)

assay

>95% (SDS-PAGE)

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

recombinant

expressed in HEK 293 cells

recombinant

expressed in HEK 293 cells

recombinant

expressed in NSO cells

recombinant

expressed in NSO cells

form

lyophilized powder

form

liquid

form

lyophilized powder

form

lyophilized powder

mol wt

35 kDa by SDS-PAGE (glycosylated form, under reducing conditions), 32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions)

mol wt

~150 kDa by SDS-PAGE

mol wt

66 kDa by SDS-PAGE, 66 kDa by SDS-PAGE (reducing and non-reducing conditions)

mol wt

30 kDa by SDS-PAGE (reducing), 65 kDa by SDS-PAGE (reducing) (doublet)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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