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S8689

Fas Ligand, soluble human

recombinant, expressed in HEK 293 cells, lyophilized powder

Synonym(s):

SuperFas Ligand™

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5 μg

Available to ship TODAYfromMILWAUKEE

$954.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.56
MDL number:
MFCD01092558
Form:
lyophilized powder
Assay:
≥95% (SDS-GE)
Biological source:
human
Recombinant:
expressed in HEK 293 cells
Mol wt:
32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions), 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions)

$954.00

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biological source

human

Quality Segment

200

recombinant

expressed in HEK 293 cells

assay

≥95% (SDS-GE)

form

lyophilized powder

mol wt

32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions), 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions)

technique(s)

ligand binding assay: suitable

UniProt accession no.

P48023

storage temp.

−20°C

Gene Information

human ... FASLG(356)

Application

ED50 = 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFas Ligand™ recognizes its receptor Fas (CD95) of the following species: human, rat, mouse.

Biochem/physiol Actions

Fas ligand has also been shown to be involved in the activation of non-apoptotic pathways including proliferation and NF-κ B activation. [1]
Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1).

Legal Information

SuperFas Ligand is a trademark of Alexis Biochemicals Corp.

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Fas Ligand, soluble human recombinant, expressed in HEK 293 cells, lyophilized powder

Sigma-Aldrich

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GITRL, Soluble mouse recombinant, expressed in HEK 293 cells, FLAG® tagged, >90% (SDS-PAGE)

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Angiopoietin-2 human >97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Sigma-Aldrich

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Angiopoietin-2 human

IL-1 Receptor Type I (human): FC (human) recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

Sigma-Aldrich

SRP8032

IL-1 Receptor Type I (human): FC (human)

assay

≥95% (SDS-GE)

assay

>90% (SDS-PAGE)

assay

>97% (SDS-PAGE)

assay

>95% (SDS-PAGE)

biological source

human

biological source

mouse

biological source

human

biological source

human

recombinant

expressed in HEK 293 cells

recombinant

expressed in HEK 293 cells

recombinant

expressed in NSO cells

recombinant

expressed in HEK 293 cells

technique(s)

ligand binding assay: suitable

technique(s)

-

technique(s)

-

technique(s)

-

form

lyophilized powder

form

liquid

form

lyophilized powder

form

lyophilized

mol wt

32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions), 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions)

mol wt

~22 kDa by SDS-PAGE

mol wt

66 kDa by SDS-PAGE (reducing and non-reducing conditions)

mol wt

~80 kDa by SDS-PAGE

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000506537
0000506537
0000447598
0000447597
0000447597

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Related Content

Data Sheet - S8689

Instructions

Global Trade Item Number

SKUGTIN
S8689-5UG04061838072108

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