Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

S9442

Anti-Synaptopodin (SE-19) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
200 μL

Available to ship TODAYfromMILWAUKEE

$627.00
$532.95

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD05865391
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ARR, WB
Citations:
18

$532.95

List Price$627.00Save 15%
Web-Only Promotion

Available to ship TODAYDetails

​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 100 kDa

species reactivity

rat

technique(s)

microarray: suitable, western blot: 1:3,000 using cytosolic S1 fraction of rat brain

UniProt accession no.

Q9Z327

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SYNPO(11346)
rat ... Synpo(60324)

General description

Synaptopodin is a proline-rich, actin-associated protein (100 kDa) is present in the post-synaptic density (PSD) in actin cytoskeleton. It is also present in the dendritic spines and differentiated podocytes. Synaptopodin contains a high amount of proline residues (~20%), which are evenly distributed along the protein sequence, thus virtually excluding the formation of globular domains. In particular, synaptopodin does not contain functional domains found in receptor clustering PSD proteins. Sequence comparison between human and mouse synaptopodin shows 84% identity. The exclusive site of synaptopodin expression in the telencephalon is restricted to specific areas of high synaptic plasticity, i.e. in the perykaria of the olfactory bulb, striatum, and hippocampus.

Immunogen

synthetic peptide corresponding to amino acids 184-202 of rat synaptopodin conjugated to KLH. This rat synaptopodin sequence has ~70% identity with human synaptopodin.

Application

Anti-Synaptopodin (SE-19) antibody produced in rabbit has been used in:
  • immunofluorescence microscopy
  • immunohistochemistry
  • western blotting

Biochem/physiol Actions

Synaptopodin is thought to play an important role in synaptic plasticity and is associated in the modulation of motility of actin in neuronal dendritic spines. The association of synaptopodin with the specialized actin system of renal podocyte foot processes suggests that it may play a role in actin cytoskeleton dynamics of these cellular extensions. Synaptopodin has been found to interact with α-actinin-4 and the tight junction protein Membrane-associated guanylate kinase inverted 1 (MAGI-1) in Madin-Darby Canine Kidney (MDCK) cells.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
M2694N7155V2514
Anti-Synaptopodin (SE-19) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution

Sigma-Aldrich

S9442

Anti-Synaptopodin (SE-19) antibody produced in rabbit

Anti-Munc-18-1 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution

Sigma-Aldrich

M2694

Anti-Munc-18-1 antibody produced in rabbit

Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution

Sigma-Aldrich

N7155

Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit

Anti-VGLUT2 (HY-19) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution

Sigma-Aldrich

V2514

Anti-VGLUT2 (HY-19) antibody produced in rabbit

description

IgG fraction of antiserum, buffered aqueous solution

description

IgG fraction of antiserum, buffered aqueous solution

description

IgG fraction of antiserum, buffered aqueous solution

description

IgG fraction of antiserum, buffered aqueous solution

antibody form

IgG fraction of antiserum

antibody form

IgG fraction of antiserum

antibody form

IgG fraction of antiserum

antibody form

IgG fraction of antiserum

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

mol wt

antigen 100 kDa

mol wt

antigen 67 kDa

mol wt

antigen 150-160 kDa

mol wt

antigen 65 kDa

Still not finding the right product?

Try our Product Selector Tool to narrow your options

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H412

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters