Skip to Content
MilliporeSigma

Skip To

S9564

Amyloid Precursor Protein α, Secreted human

>90% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), buffered aqueous solution

Synonym(s):

sAPPα

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
25 μg
Check Cart for Availability
$687.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:

$687.00


Check Cart for Availability

Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


recombinant

expressed in E. coli (N-terminal histidine tagged)

Quality Segment

assay

>90% (SDS-PAGE)

form

buffered aqueous solution

mol wt

~100 kDa by SDS-PAGE

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... APP(351)

General description

The APP (amyloid precursor protein) gene is mapped to human chromosome 21q21.3. It encodes a integral membrane protein. APPα is a soluble protein generated by sequential cleavage with α and γ secretase.

Application

Human amyloid precursor protein α secreted, has been used in enzyme linked immunosorbent assay (ELISA).

Biochem/physiol Actions

Amyloid precursor protein α is an α-secretase-cleaved soluble protein that has been shown to have neuroprotective properties. It is derived from amyloid precursor protein. The protein consists of 612 amino acids. Several G protein-coupled receptors are known to activate α-secretase-dependent processing of APP. It has neuroprotective, neurogenic and neurotrophic functions. Amyloid precursor protein a also stimulates gene expression and protein expression.

Physical form

Solution 0.2 μm filtered, in phosphate buffered saline, pH 7.4.

Preparation Note

Expressed as a soluble protein and purified under non-denaturing conditions.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
S4316A2201F2053
description

>90% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), buffered aqueous solution

description

recombinant, expressed in E. coli (N-terminal histidine tagged), solution

description

≥95% (HPLC)

description

>90% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), buffered aqueous solution

recombinant

expressed in E. coli (N-terminal histidine tagged)

recombinant

expressed in E. coli (N-terminal histidine tagged)

recombinant

-

recombinant

expressed in E. coli (N-terminal histidine tagged)

assay

>90% (SDS-PAGE)

assay

-

assay

≥95% (HPLC)

assay

>90% (SDS-PAGE)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

buffered aqueous solution

form

solution

form

powder

form

buffered aqueous solution

mol wt

~100 kDa by SDS-PAGE

mol wt

~100 kDa by SDS-PAGE

mol wt

-

mol wt

>18.8 kDa

shipped in

dry ice

shipped in

dry ice

shipped in

-

shipped in

dry ice


Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters