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SAB4200224

Anti-phospho-TDP-43 (pSer410) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

Synonym(s):

Anti-phospho-ALS10, Anti-phospho-TAR DNA binding protein 43, Anti-phospho-TARDBP, Anti-phospho-TARDP43

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200 μL

Available to ship TODAYfromMILWAUKEE

$603.00

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
7

$603.00

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~43 kDa

species reactivity

mouse, human

concentration

~1.0 mg/mL

technique(s)

western blot: 1-2 μg/mL using HepG2 and NIH3T3 cell lysates

UniProt accession no.

Q13148

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer410)

Gene Information

human ... TARDBP(23435)
mouse ... Tardbp(230908)

General description

TDP-43 (TAR DNA binding protein) belongs to the family of heterogeneous nuclear ribonucleoproteins (hnRNPs), that binds single stranded RNA. TDP-43 has been implicated in the transcription regulation of HIV. TDP-43 is the major ubiquinated component of cytoplasmic inclusions in frontotemporal lobe degeneration subtype FTLD-U and amyotrophic lateral sclerosis (ALS). TDP-43 is predominantly localized to the nucleus.

Immunogen

synthetic peptide containing phosphorylated Ser410 of human TDP-43, conjugated to KLH. The corresponding sequence is identical in mouse TDP-43.

Application

Anti-phospho-TDP-43 (pSer410) antibody produced in rabbit has been used in immunoblotting.

Biochem/physiol Actions

Pathological TDP-43 forms abnormal inclusions in neuronal perikarya and neurites. Several pathogenic TDP-43 mutations have been identified in familial amyotrophic lateral sclerosis (ALS).

Physical form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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SAB4200223T1705MABN774
Anti-phospho-TDP-43 (pSer410) antibody produced in rabbit ~1.0 mg/mL, affinity isolated antibody

Sigma-Aldrich

SAB4200224

Anti-phospho-TDP-43 (pSer410) antibody produced in rabbit

Anti-phospho-TDP-43 [pSer409] antibody produced in rabbit ~1.0 mg/mL, affinity isolated antibody

Sigma-Aldrich

SAB4200223

Anti-phospho-TDP-43 [pSer409] antibody produced in rabbit

Anti-TDP-43 antibody produced in rabbit ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

T1705

Anti-TDP-43 antibody produced in rabbit

Anti-TDP-43 Antibody, clone DB9 clone DB9, from mouse

Sigma-Aldrich

MABN774

Anti-TDP-43 Antibody, clone DB9

description

~1.0 mg/mL, affinity isolated antibody

description

~1.0 mg/mL, affinity isolated antibody

description

~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution

description

clone DB9, from mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

Gene Information

human ... TARDBP(23435)
mouse ... Tardbp(230908)

Gene Information

human ... TARDBP(23435)
mouse ... Tardbp(230908)

Gene Information

human ... TARDBP(23435)

Gene Information

human ... TARDBP(23435)

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

-

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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