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Anti-Troponin T antibody, Mouse monoclonal

Name: Anti-Troponin T antibody, Mouse monoclonal
Brand: SIGMA
Price: 507 USD
Availability: InStock

clone JLT-12, purified from hybridoma cell culture

Synonym(s):

Anti-TNNT1, Anti-TNNT2

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Size/SKU	Availability	Price
100 μL	Available to ship TODAYfromMILWAUKEE	$507.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

JLT-12, monoclonal

Application:

IF, IHC

Citations:

$507.00

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified from hybridoma cell culture

antibody product type

primary antibodies

clone

JLT-12, monoclonal

form

buffered aqueous solution

mol wt

antigen ~38 kDa

species reactivity

rat, human, mouse, bovine, rabbit, goat

concentration

~1.0 mg/mL

technique(s)

immunoblotting: 0.5-1 μg/mL using rat skeletal muscle extract, immunofluorescence: suitable, immunohistochemistry: 5-10 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human skeletal muscle sections

isotype

IgG1

UniProt accession no.

P13805

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TNNT1(7138)

Description

General description

Anti-Troponin T antibody, Mouse monoclonal, (mouse IgG1 isotype) is derived from the JLT-12 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with purified Troponin T from rabbit skeletal muscle. Troponin T (TNNT) is the tropomyosin binding subunit of the troponin complex. Three genes have evolved to encode the cardiac (TNNT2), slow (TNNT1) and fast (TNNT3) skeletal muscle Troponin T proteins, which are specifically expressed in cardial, slow and fast skeletal muscles, respectively.

Immunogen

purified Troponin T from rabbit skeletal muscle

Application

Anti-Troponin T antibody, Mouse monoclonal has been used in:
immunoblotting
immunofluorescence
immunohistochemistry

Biochem/physiol Actions

Troponin T (TNNT) participates in calcium regulation of actin thin filament function and is required for the contraction of striated muscles. Levels of cardiac Troponin T serve as a sensitive biomarker of myocardial injury. Troponin T has also been suggested as a potential marker in diagnosis of skeletal myopathies including amyotrophic lateral sclerosis (ALS).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB4200715	MABT368	SAB4200721
Sigma-Aldrich SAB4200717 Anti-Troponin T antibody, Mouse monoclonal	Sigma-Aldrich SAB4200715 Anti-β-tubulin antibody, Mouse monoclonal	Sigma-Aldrich MABT368 Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1	Sigma-Aldrich SAB4200721 Anti-GABA antibody, Mouse monoclonal
description clone JLT-12, purified from hybridoma cell culture	description clone 2-28-33, purified from hybridoma cell culture	description clone 9C2.1, from mouse	description clone GB-69, purified from hybridoma cell culture
biological source mouse	biological source mouse	biological source mouse	biological source mouse
species reactivity rat, human, mouse, bovine, rabbit, goat	species reactivity dog, chicken, rat, bovine, monkey, human, mouse	species reactivity mouse, rat	species reactivity rat, monkey, frog, mouse, human, gerbil
antibody form purified from hybridoma cell culture	antibody form purified from hybridoma cell culture	antibody form purified immunoglobulin	antibody form purified from hybridoma cell culture
clone JLT-12, monoclonal	clone 2-28-33, monoclonal	clone 9C2.1, monoclonal	clone GB-69, monoclonal
Gene Information human ... TNNT1(7138)	Gene Information human ... TUBB(203068) mouse ... Tubb3(22152)	Gene Information human ... TNNT2(7139)	Gene Information human ... GABRA1(2554) mouse ... Gabra1(14394) rat ... Gabra1(29705) rhesus monkey ... Gabra1(574302)
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate -

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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