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SAB4200764

Anti-Dystrophin Antibody

mouse monoclonal, MANDYS8

enhanced validation

Enhanced Validation

Synonym(s):

Anti-DMD

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Size/SKUAvailabilityPrice
100 μL

Available to ship TODAYfromMILWAUKEE

$534.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Clone:
MANDYS8, monoclonal
Species reactivity:
porcine, rabbit, mouse, rat, human
Application:
IHC
Citations:
3

$534.00


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Product Name

Anti-Dystrophin antibody, Mouse monoclonal, clone MANDYS8, purified from hybridoma cell culture

biological source

mouse

Quality Segment

antibody form

purified from hybridoma cell culture

antibody product type

primary antibodies

clone

MANDYS8, monoclonal

form

buffered aqueous solution

mol wt

~427 kDa

species reactivity

porcine, rabbit, mouse, rat, human

enhanced validation

independent
Learn more about Antibody Enhanced Validation

concentration

~1.0 mg/mL

technique(s)

immunoblotting: suitable, immunohistochemistry: 5-10 μg/mL using acetone fixed rat tongue frozen sections

isotype

IgG2b

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DMD(1756)

General description

Anti-Dystrophin antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with fragment of recombinant human dystrophin. Dystrophin is a 427 kD protein which joins the actin cytoskeleton to laminin. It possesses multiple domains and is localized to the extracellular matrix. Dystrophin contains NH2-terminal domain for actin binding. The C-terminal domain interacts with dystrophin associated protein (DAP).
Dystrophin is a rod-shaped cytoskeletal protein located to the periphery (plasma membrane) of normal striated muscle fibers.

Immunogen

recombinant human dystrophin

Application

Anti-Dystrophin antibody, Mouse monoclonal has been used in immunoblotting and immunohistochemistry.

Biochem/physiol Actions

Anti-Dystrophin antibody, Mouse monoclonal specifically recognizes an epitope located on the rod domain of the human dystrophin molecule.
Dystrophin is known to prevent muscle fibre injury due to contraction.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.

Other Notes

This product is for R&D use only, not for drug, household, or other uses.

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clone MANDYS8, purified from hybridoma cell culture

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clone MANDYS8, ascites fluid

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clone 2C6 (MANDYS106), from mouse

description

clone BDNF129-13, purified from hybridoma cell culture

clone

MANDYS8, monoclonal

clone

MANDYS8, monoclonal

clone

2C6 (MANDYS106), monoclonal

clone

BDNF129-13, monoclonal

species reactivity

porcine, rabbit, mouse, rat, human

species reactivity

chicken, rat, human, pig, rabbit, mouse

species reactivity

human

species reactivity

human

Gene Information

human ... DMD(1756)

Gene Information

human ... DMD(1756)
mouse ... Dmd(13405)
rat ... Dmd(24907)

Gene Information

human ... DMD(1756)

Gene Information

human ... BDNF(627)

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

purified from hybridoma cell culture

antibody form

ascites fluid

antibody form

purified antibody

antibody form

purified from hybridoma cell culture

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200


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Storage Class

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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