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Anti-α-Synuclein (SNCA) Antibody

Name: Anti-α-Synuclein (SNCA) Antibody
Brand: SIGMA
Price: 560 USD
Availability: InStock

rabbit polyclonal

Synonym(s):

α-synuclein, NACP, Non-A β component of AD amyloid, Non-A4 component of amyloid precursor, SNCA

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Size/SKU	Availability	Price
100 μg	Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)	$560.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD02095740

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA, WB

Citations:

$560.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

A recombinant, preservative-free antibody is available for your target. Try ZRB1134

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Properties

Product Name

Anti-Synuclein-α antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 14 kDa

species reactivity

mouse, rat, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000, western blot: 1:500-1:1000

NCBI accession no.

P37840

UniProt accession no.

P37840

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SNCA(6622)

Description

General description

Anti-Synuclein-α antibody detects endogenous levels of total Synuclein-α protein.

The SNCA (synuclein α) gene is mapped to human chromosome 4q22.1.

Immunogen

The antiserum was produced against synthesized peptide derived from human Synuclein-alpha.

Immunogen Range: 86-135

Biochem/physiol Actions

Accumulation of α-synuclein in oligodendrocytes results in the loss of myelin and causes neurodegeneration, leading to multiple system atrophy. Synuclein-α is known to induce oligodendrocyte maturation. The encoded protein is considered to be an important aggregate of Lewy bodies, contributing to the pathogenesis of Parkinson disease.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

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This Item	SAB4503996	HPA005459	WH0006622M1
Sigma-Aldrich SAB4502829 Anti-Synuclein-α antibody produced in rabbit	Sigma-Aldrich SAB4503996 Anti-phospho-Synuclein (pSer¹²⁹) antibody produced in rabbit	Sigma-Aldrich HPA005459 Anti-SNCA antibody produced in rabbit	Sigma-Aldrich WH0006622M1 Monoclonal Anti-SNCA antibody produced in mouse
description affinity isolated antibody	description affinity isolated antibody	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description clone 2E4, purified immunoglobulin, buffered aqueous solution
biological source rabbit	biological source rabbit	biological source rabbit	biological source mouse
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form purified immunoglobulin
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
Gene Information human ... SNCA(6622)	Gene Information human ... SNCA(6622)	Gene Information human ... SNCA(6622)	Gene Information human ... SNCA(6622)

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c