SBVT20
SB-ratMdr1b-Sf9-HAM
recombinant, expressed in baculovirus infected Sf9 cells
Synonym(s):
Mdr1b, Mdr1b rat membrane vesicles, P-glycoprotein, P-gp, multidrug resistance protein 1b, rat Abcb1b
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 ea | Ships in 4 Weeks. | $827.00 |
About This Item
recombinant
expressed in baculovirus infected Sf9 cells
form
liquid
packaging
pkg of 500 μL
concentration
5 mg/mL
shipped in
dry ice
storage temp.
−70°C
Gene Information
rat ... Abcb1b(24646)
General description
Application
The standard vesicular transport assay is an inhibitory assay performed with cold test articles. This assay provides information on any interaction between the ABC transporter and the test article. The transport of the reporter substrate is measured in the presence of the test article (typically in 7 concentrations) and IC50 is defined as the concentration inhibiting the transport of the reporter substrate by 50%.
Should radiolabeled form of the investigated compound or adequate analytical methods (LC/MS, HPLC) be available, the vesicular transport assay may be performed in a direct format without the reporter substrate and may identify substrate nature of the test article. The vesicular transport substrate assay is a low throughput assay. It is suitable for low permeability test compounds as high permeability compounds may escape from the vesicles through the lipid bilayer.
Physical form
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| description recombinant, expressed in baculovirus infected Sf9 cells | description membrane preparation for Vesicular Transport Assays, recombinant, expressed in baculovirus infected Sf9 cells | description recombinant, expressed in HEK 293 cells | description MRP2 rat vesicles |
| recombinant expressed in baculovirus infected Sf9 cells | recombinant expressed in baculovirus infected Sf9 cells | recombinant expressed in HEK 293 cells | recombinant expressed in HEK 293 cells |
| concentration 5 mg/mL | concentration 5 mg/mL | concentration 5 mg/mL | concentration 5 mg/mL |
| form liquid | form liquid | form liquid | form liquid |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
| storage temp. −70°C | storage temp. −70°C | storage temp. −70°C | storage temp. −70°C |
| Gene Information rat ... Abcb1b(24646) | Gene Information human ... ABCC2(1244) | Gene Information mouse ... Abcb1a(18671) | Gene Information rat ... Abcc2(25303) |
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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