Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

SMB00311

Shogaol

≥90% (HPLC)

Synonym(s):

[6]-Shogaol, (6)-Shogaol, 1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
50 mg

Estimated to ship onOctober 22, 2026fromMILWAUKEE

$1,120.00

About This Item

Empirical Formula (Hill Notation):
C17H24O3
CAS Number:
555-66-8
Molecular Weight:
276.37
UNSPSC Code:
12352205
NACRES:
NA.25
PubChem Substance ID:
329824943
MDL number:
MFCD01736094
Beilstein/REAXYS Number:
2056098

$1,120.00

Estimated to ship onOctober 22, 2026Details

​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Segment

assay

≥90% (HPLC)

form

liquid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

CCCCC\C=C\C(=O)CCc1ccc(O)c(OC)c1

InChI

1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+

InChI key

OQWKEEOHDMUXEO-BQYQJAHWSA-N

General description

Shogaol or 6-shogaol, the pungent metabolite of dried ginger, is one of the main bioactive compounds extracted from the natural dietary rhizome, Zingiber officinale Roscoe (ginger). It is the dehydrated successor of 6-gingerol with an α,β-unsaturated ketone skeleton.

Application

Shogaol has been used to determine its safe dose to evaluate potential toxicity in higher concentrations in mice models. It has also been used to investigate its antioxidant effects on the modulation of TRPC5 (ITRPC5) and TRPA1 (ITRPA1) currents.

Biochem/physiol Actions

Shogaols exhibits higher potency, efficacy, and biological activities than gingerols. It is an excellent antioxidant agent, that protects human primary epidermal melanocytes against oxidative stress by activating nuclear factor E2-related factor (Nrf2)-antioxidant response. Shogaol also displays antimicrobial, antifungal, and anti-biofilm activities against Candida albicans, and Candida auris. It exerts anti-inflammatory properties and protects against abdomen irradiation (ABI)-induced intestinal side effects. 6-shogaol also inhibits lipopolysaccharide (LPS)-induced inflammation via peroxisome proliferator-activated receptor gamma (PPAR-γ) activation.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
PHL8979239303PHL83910
Shogaol ≥90% (HPLC)

Sigma-Aldrich

SMB00311

Shogaol

6-Shogaol phyproof® Reference Substance

PHL89792

6-Shogaol

[6]-Shogaol analytical standard

Supelco

39303

[6]-Shogaol

8-Shogaol phyproof® Reference Substance

PHL83910

8-Shogaol

description

≥90% (HPLC)

description

phyproof® Reference Substance

description

analytical standard

description

phyproof® Reference Substance

assay

≥90% (HPLC)

assay

≥90.0% (HPLC)

assay

≥90.0% (HPLC)

assay

≥90.0% (HPLC)

form

liquid

form

-

form

-

form

-

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

-

application(s)

food and beverages

application(s)

food and beverages

Quality Level

200

Quality Level

-

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Codes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters