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SMB00348

Ginsenoside Compound K

≥96% (HPLC)

Synonym(s):

(3B,12B)-3,12-Dihydroxydammar-24-en-20-yl β-D-glucopyranoside, 20(S)-Ginsenoside Ck, Ginsenoside K, Protopanaxadiol 20-O-glucoside

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$242.00
$181.50

About This Item

Empirical Formula (Hill Notation):
C36H62O8
CAS Number:
Molecular Weight:
622.87
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.25

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Quality Segment

assay

≥96% (HPLC)

form

powder

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

SMILES string

CC(C)=CCC[C@](C1C2[C@H](O)CC3[C@@]([C@]2(C)CC1)(C)CCC4C(C)(C)[C@@H](O)CC[C@@]43C)(C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O

InChI

1S/C36H62O8/c1-20(2)10-9-14-36(8,44-31-30(42)29(41)28(40)23(19-37)43-31)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(39)32(3,4)24(33)12-17-34(25,35)6/h10,21-31,37-42H,9,11-19H2,1-8H3/t21?,22-,23-,24?,25?,26+,27?,28-,29+,30-,31+,33+,34-,35-,36+/m1/s1

InChI key

FVIZARNDLVOMSU-KJULZEBLSA-N

General description

Ginsenoside Compound K is a tetracyclic dammarane-type triterpenoid saponin found in the roots of Panax ginseng. It is a major constituent in ginseng, which has been traditionally used to increase resistance to stress and aging.

Application


  • Combination of Electrochemistry and Mass Spectrometry to Study Nitric Oxide Metabolism and Its Modulation by Compound K in Breast Cancer Cells.: This research explores the interaction of Ginsenoside Compound K with nitric oxide metabolism in breast cancer cells, employing a combination of electrochemical techniques and mass spectrometry to elucidate the metabolic pathways and potential therapeutic effects of Compound K (Zhao et al., 2022).

  • Metabolic analysis of Panax notoginseng saponins with gut microbiota-mediated biotransformation by HPLC-DAD-Q-TOF-MS/MS.: This article investigates the gut microbiota-mediated biotransformation of Panax notoginseng saponins, including Compound K, detailing the complex interactions and metabolic profiles in a biological system, which could inform their therapeutic use and bioavailability (Chen et al., 2018).

Biochem/physiol Actions

Ginsenoside compound K has many pharmacological properties that include anti-diabetic, anti-inflammatory, hepatoprotective, anti-allergic, and anti-carcinogenic effects. It also displays neuroprotective properties, in mice it has shown recovery from synaptic loss and memory impairment. Ginsenoside K can inhibit several gene expressions in human umbilical vein endothelial cells (HUVECs), resulting in the inhibition of migration and angiogenesis of endothelial cells.

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This Item
SMB003474498768317
description

≥96% (HPLC)

description

≥98% (HPLC)

description

analytical standard

description

analytical standard

form

powder

form

powder

form

-

form

-

assay

≥96% (HPLC)

assay

≥98% (HPLC)

assay

≥98.0% (HPLC)

assay

≥90% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

food and beverages

application(s)

food and beverages


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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