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SML0006

CK-666

≥98% (HPLC), powder, Arp2/3 comple inhibitor

Synonym(s):

2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]-benzamide, CK 666, CK-0944666

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Size/SKUAvailabilityPrice
5 mg
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$151.00
25 mg
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$568.00

About This Item

Empirical Formula (Hill Notation):
C18H17FN2O
CAS Number:
Molecular Weight:
296.34
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$151.00


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Product Name

CK-666, ≥98% (HPLC), powder

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

DMSO: ≥25 mg/mL

storage temp.

2-8°C

SMILES string

Cc1[nH]c2ccccc2c1CCNC(=O)c3ccccc3F

InChI

1S/C18H17FN2O/c1-12-13(14-6-3-5-9-17(14)21-12)10-11-20-18(22)15-7-2-4-8-16(15)19/h2-9,21H,10-11H2,1H3,(H,20,22)

InChI key

UXRKUKRXVWJFER-UHFFFAOYSA-N

Application

CK-666 may be used to study Arp2/3-mediated structural changes in cells.

Biochem/physiol Actions

CK-666 is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex.
CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex and prevents its movement into active conformation.

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This Item
182515C7374C9124
description

≥98% (HPLC), powder

description

Arp2/3 Complex Inhibitor I, CK-666, CAS 442633-00-3, is a cell-permeable selective inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex (IC50 = 4 uM in human).

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

solid

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: ≥25 mg/mL

solubility

DMSO: 50 mg/mL

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 10 mg/mL, clear

color

white to tan

color

off-white

color

peach to light pink

color

white to light gray


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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