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SML0047

MoTP

≥98% (HPLC)

Synonym(s):

33N14, 4-(4-Morpholinobutylthio)phenol

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$113.00
$96.05
25 mg

Available to ship TODAYfromMILWAUKEE

$352.00

About This Item

Empirical Formula (Hill Notation):
C14H21NO2S
CAS Number:
Molecular Weight:
267.39
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$96.05

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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

DMSO: ≥80 mg/mL

storage temp.

−20°C

SMILES string

Oc1ccc(SCCCCN2CCOCC2)cc1

InChI

1S/C14H21NO2S/c16-13-3-5-14(6-4-13)18-12-2-1-7-15-8-10-17-11-9-15/h3-6,16H,1-2,7-12H2

InChI key

YHKNLUTUXZDOQI-UHFFFAOYSA-N

Application

MoTP may be used in cell signaling and differentiation studies.

Biochem/physiol Actions

Melanocytotoxic; reversibly blocks the specification of neural crest cells into melanocytes
MoTP (also known as 33N14) reversibly blocks the specification of neural crest cells into melanocytes in zebrafish studies. Differentiation of neural crest cell-derived melanoblasts proceeds to late developmental stages, but they fail to reach the terminal stage of melanin production and die. Melanocytotoxicity is dependent on tyrosinase activity which convert it into a toxic form. MoTP specifically ablates only cells that express tyrosinase at high levels, which in the embryo are limited to melanoblasts and newly formed melanocytes. MoTP should be a useful tool for elucidating melanocyte stem cell regeneration, recruitment, and maintenance.

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This Item
SML1145SML2221H6278
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥70% Z isomer (remainder primarily E-isomer)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

300

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

DMSO: ≥80 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

methanol: 10 mg/mL, ethanol: 20 mg/mL (with heating)

color

white to tan

color

white to beige

color

white to beige

color

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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