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SML0056

Cefotiam dihydrochloride hydrate

≥98% (HPLC)

Synonym(s):

(6R,7R)-7-[[2-(2-Amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]-thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrochloride hydrate

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Size/SKUAvailabilityPrice
50 mg

Available to ship TODAYfromMILWAUKEE

$260.00

About This Item

Empirical Formula (Hill Notation):
C18H23N9O4S3 · 2HCl · xH2O
CAS Number:
Molecular Weight:
598.55 (anhydrous basis)
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

$260.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to tan

solubility

H2O: ≥22 M

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[s]1c(nc(c1)CC(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)CSc4[n](nnn4)CCN(C)C)N.[Cl-].[Cl-].[H+].[H+]

InChI

1S/C18H23N9O4S3.2ClH/c1-25(2)3-4-26-18(22-23-24-26)34-7-9-6-32-15-12(14(29)27(15)13(9)16(30)31)21-11(28)5-10-8-33-17(19)20-10;;/h8,12,15H,3-7H2,1-2H3,(H2,19,20)(H,21,28)(H,30,31);2*1H/t12-,15-;;/m1../s1

InChI key

BWRRTAXZCKVRON-DGPOFWGLSA-N

General description

Chemical structure: β-lactam

Application

Cefotiam dihydrochloride hydrate is used as broad-spectrum antibiotic.

Biochem/physiol Actions

Cefotiam, a derivative of cephalosporin, exhibits broad-spectrum anti-bacterial activity. It inhibits the cross-linking stage of peptidoglycan and blocks the synthesis of bacterial cell wall. It is resistant to β-lactamases.
Cefotiam is a second generation cephalosporin antibiotic which has been used as a prophylatic antibiotic for MRSA.
Second generation cephalosporin, prophylatic antibiotic for MRSA

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This Item
C4292C7912C7039
description

≥98% (HPLC)

description

870 - 1015 μg/mg anhydrous basis

description

potency: 916-964 μg per mg

description

suitable for plant cell culture, BioReagent, powder or crystals

form

powder

form

powder or crystals

form

powder

form

powder or crystals

assay

≥98% (HPLC)

assay

870-1015 μg/mg (anhydrous basis)

assay

-

assay

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

solubility

H2O: ≥22 M

solubility

-

solubility

H2O: 50 mg/mL

solubility

H2O: 10% ( )


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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