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SML0147

Drospirenone

≥98% (HPLC)

Synonym(s):

6β,7β:15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone, Dihydrospirorenone

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10 mg
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$108.00
50 mg
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$419.00

About This Item

Empirical Formula (Hill Notation):
C24H30O3
CAS Number:
67392-87-4
Molecular Weight:
366.49
NACRES:
NA.77
PubChem Substance ID:
329825195
UNSPSC Code:
51111800
EC Number:
266-679-2
MDL number:
MFCD00867350
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

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Quality Segment

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -180 to -195°, c = 1 in methanol

storage condition

desiccated

color

white to tan

solubility

DMSO: ≥15

originator

Bayer

storage temp.

2-8°C

SMILES string

C[C@]12CCC(=O)C=C1[C@@H]3C[C@@H]3[C@@H]4[C@@H]2CC[C@@]5(C)[C@H]4[C@@H]6C[C@@H]6[C@@]57CCC(=O)O7

InChI

1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1

InChI key

METQSPRSQINEEU-HXCATZOESA-N

Gene Information

human ... NR3C2(4306), PGR(5241)

Application

Drospirenone was tested for genotoxicity in rat and human hepatocytes.[1]
Drospirenone has been used as a progestogen agent in pond snail and fish.[2]

Biochem/physiol Actions

Drospirenone is a fourth-generation progestin that has antimineralocorticoid, and antiandrogenic activity in addition to potent progestogenic activity. In two recent studies drospirenone appeared to double the risk of venous thromboembolism compared to levonorgestrel, although other studies found little added risk.
Fourth-generation progestin; contraceptive

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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1 of 1

This Item
1229409Y0001105Y0001718
Drospirenone ≥98% (HPLC)

Sigma-Aldrich

SML0147

Drospirenone

Drospirenone United States Pharmacopeia (USP) Reference Standard

USP

1229409

Drospirenone

Drospirenone European Pharmacopoeia (EP) Reference Standard

Y0001105

Drospirenone

Drospirenone for peak identification European Pharmacopoeia (EP) Reference Standard

Y0001718

Drospirenone for peak identification

form

powder

form

-

form

-

form

-

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

solubility

DMSO: ≥15

solubility

-

solubility

-

solubility

-

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000433220
0000433220
0000197799
0000175245
0000162924

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Nuclear Receptors (Steroids)

We offers many products related to Nuclear Receptors (Steroids) for your research needs.

Global Trade Item Number

SKUGTIN
SML0147-10MG04061832867885
SML0147-50MG04061832867892

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