SML0211
iCRT3
≥98% (HPLC), Wnt / b-catenin pathway inhibitor, powder
Synonym(s):
2-[[[2-(4-ethylphenyl)-5-methyl-4-oxazolyl]methyl]thio]-N-(2-phenylethyl)acetamide
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $143.00 |
25 mg | Check Cart for Availability | $567.00 |
About This Item
Product Name
iCRT3,
assay
≥98% (HPLC)
Quality Segment
form
powder
storage condition
desiccated
color
white to tan
solubility
DMSO: ≥5 mg/mL
storage temp.
2-8°C
SMILES string
CCc1ccc(cc1)-c2nc(CSCC(=O)NCCc3ccccc3)c(C)o2
InChI
1S/C23H26N2O2S/c1-3-18-9-11-20(12-10-18)23-25-21(17(2)27-23)15-28-16-22(26)24-14-13-19-7-5-4-6-8-19/h4-12H,3,13-16H2,1-2H3,(H,24,26)
InChI key
QTDYVSIBWGVBKU-UHFFFAOYSA-N
General description
Application
- for β- catenin inhibition in dual luciferase assay
- to inhibit β-catenin /TCF interactions and their transcriptional activity
- as wingless/tailess (wnt) antagonist, to determine Wnt/β-catenin signaling is essential for PROX1-mediated regulation of forkhead box protein C2 (FOXC2)(3)catenin inhibition in dual luciferase assay
- to inhibit β- catenin /TCF interactions and their transcriptional activity
- as wingless/tailess (wnt) antagonist, to determine Wnt/β-catenin signaling is essential for PROX1-mediated regulation of forkhead box protein C2 (FOXC2)
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description - | description The β-Catenin/Tcf Inhibitor III, iCRT3 controls the biological activity of β-Catenin/Tcf. This small molecule/inhibitor is primarily used for Biochemicals applications. | description ≥98% (HPLC) | description ≥95% (HPLC) |
| assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay ≥95% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. room temp |
| solubility DMSO: ≥5 mg/mL | solubility DMSO: 50 mg/mL | solubility DMSO: ≥5 mg/mL | solubility DMSO: 5 mg/mL, clear (warmed) |
| storage condition desiccated | storage condition OK to freeze, protect from light | storage condition - | storage condition - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
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