SML0228
Rc-Ome
≥98% (HPLC)
Synonym(s):
(2E)-3-(2-hydroxy-5-methoxyphenyl)-1-(4-methoxyphenyl)-2-Propen-1-one, trans-6,4′-dimethoxyretrochalcone
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| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Check Cart for Availability | $216.00 |
About This Item
Empirical Formula (Hill Notation):
C17H16O4
CAS Number:
Molecular Weight:
284.31
NACRES:
NA.77
UNSPSC Code:
12352202
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
, light to dark yellow
solubility
DMSO: ≥10 mg/mL
storage temp.
2-8°C
Application
Rc-Ome may be used in GABAA-mediated cell signaling studies.
Biochem/physiol Actions
Rc-OMe is a GABAA PAM
Rc-OMe is a GABAA PAM that distinguishes α1β2γ2s from α1β2 receptors. The compound has very weak potentiating effects on α1β2, but potentiates GABA-elicited currents of α(123)β2γ2s receptors, all with low μM EC50s. Rc-OMe acts at a binding site that is distinct from BDZ, pentobarbital and loreclezole modulatory sites.
Features and Benefits
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥97% (HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥97% (HPLC) |
| form powder | form powder | form powder | form lyophilized powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: ≥10 mg/mL | solubility DMSO: 2 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 5 mg/mL, clear (warmed) |
| color , light to dark yellow | color yellow to orange | color white to beige | color white |
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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