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SML0371

MLR-1023

≥98% (HPLC), Lyn kinase activator, powder

Synonym(s):

5-(3-Methylphenoxy)- 2(1H)-pyrimidinone, CP 26154, NSC 314335, Tolimidone

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Size/SKUAvailabilityPrice
25 mg

Available to ship TODAYfromMILWAUKEE

$419.00
$356.15

About This Item

Empirical Formula (Hill Notation):
C11H10N2O2
CAS Number:
Molecular Weight:
202.21
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$356.15

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Product Name

MLR-1023, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL (clear solution)

storage temp.

room temp

SMILES string

Cc1cccc(OC2=CNC(=O)N=C2)c1

InChI

1S/C11H10N2O2/c1-8-3-2-4-9(5-8)15-10-6-12-11(14)13-7-10/h2-7H,1H3,(H,12,13,14)

InChI key

HJQILFPVRNHTIG-UHFFFAOYSA-N

Biochem/physiol Actions

MLR-1023 is a potent, orally active, allosteric activator of the non-receptor Src-related Lyn kinase that produces lasting glucose lowering, reduces HbA1c levels, and preserves pancreatic β-cells in db/db mice. MLR-1023 increased insulin receptor sensitivity. MLR-1023 (Tolimidone) is antiulcer agent.
MLR-1023 is a potent, orally active, allosteric activator of the non-receptor Src-related Lyn kinase; insulin receptor-potentiating agent; antiulcer agent.
MLR-1023 has a therapeutic potential to treat type 2 diabetes.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
SML0220SML0218C0494
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥97% (HPLC), white, powder

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

solubility

DMSO: 15 mg/mL (clear solution)

solubility

DMSO: 5 mg/mL (clear solution)

solubility

DMSO: ≥5 mg/mL (warm DMSO)

solubility

DMSO: ≥10 mg/mL

color

white to beige

color

white to beige

color

white to beige

color

white


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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