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SML0391

SB-268262

≥98% (HPLC)

Synonym(s):

(+/-)-SB-273779, N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide

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Size/SKUAvailabilityPrice
25 mg

Estimated to ship TODAYfromMILWAUKEE

$376.00

About This Item

Empirical Formula (Hill Notation):
C18H15N3O4S2
CAS Number:
Molecular Weight:
401.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$376.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: >5 mg/mL

storage temp.

2-8°C

SMILES string

CN(C(=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)c2nccs2)c3ccccc3C

InChI

1S/C18H15N3O4S2/c1-12-5-3-4-6-14(12)20(2)17(22)13-7-8-16(15(11-13)21(23)24)27(25)18-19-9-10-26-18/h3-11H,1-2H3

InChI key

YXHLPJQQPOMPGE-UHFFFAOYSA-N

Biochem/physiol Actions

SB-268262 is a selective non-peptide antagonist at the CGRP1 receptor.
SB-268262 is a selective non-peptide antagonist at the CGRP1 receptor. SB-268262 inhibits CGRP binding, and CGRP-mediated stimulation of adenylyl cyclase activity in human neuroblastoma cells with IC50 values of 240 and 830 nM, respectively.

Features and Benefits

This compound is featured on the Calcitonin Gene-Related Peptides page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
SML1348SML2274SML1682
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: >5 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 5 mg/mL, clear (warmed)

color

white to beige

color

white to beige

color

white to beige

color

white to beige


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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