SML0430
PR-619
≥95% (HPLC), deubiquitylating enzymes (DBUs) inhibitor, powder
Synonym(s):
2,6-Diamino-3,5-dithiocyanopyridine, Thiocyanic acid C,C′-(2,6-diamino-3,5-pyridinediyl) ester; 2,6-Diaminopyridine-3,5-bis(thiocyanate)
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Available to ship TODAYfromMILWAUKEE | $127.00 |
5 mg | Available to ship TODAYfromMILWAUKEE | $348.00 |
About This Item
Product Name
PR-619, ≥95% (HPLC)
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL (clear solution)
storage temp.
−20°C
SMILES string
Nc1nc(N)c(SC#N)cc1SC#N
InChI
1S/C7H5N5S2/c8-2-13-4-1-5(14-3-9)7(11)12-6(4)10/h1H,(H4,10,11,12)
InChI key
ZXOBLNBVNROVLC-UHFFFAOYSA-N
Application
- as a component of lysis buffer and also as a deubiquitinase inhibitor to treat proteins derived from SILAC-labeled Jurkat cells
- as a pan-deubiquitinase inhibitor to study its effect on adenoassociated virus (AAV) transduction
- in radioimmunoprecipitation assay buffer (RIPA) buffer used for ubiquitination assays
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description ≥95% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description The DUB Inhibitor V, PR-619 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. |
| assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥99% (HPLC) |
| form powder | form powder | form powder | form solid |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C |
| solubility DMSO: 5 mg/mL (clear solution) | solubility DMSO: 3 mg/mL, clear (warmed) | solubility DMSO: 20 mg/mL, clear | solubility DMSO: 50 mg/mL |
| color white to beige | color white to light brown | color white to beige | color light beige to yellow |
Storage Class
11 - Combustible Solids
wgk
WGK 3
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